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. 2013 Jul 23;8(7):e69477. doi: 10.1371/journal.pone.0069477

Figure 3. Myocardial infarction is diminished in UNC5B+/− mice.

Figure 3

A) Comparison of UNC5B protein expression in UNC5B+/− and WT animals in different organs (n = 5 per group). B) Comparison of UNC5B transcriptional mRNA levels of organs normalized to brain tissue of WT animals (n = 5 per group). C) Infarct size in UNC5B+/− mice compared with WT mice after 60 minutes of myocardial ischemia followed by 2 hours reperfusion. Calculated is the percentage of necrotic tissue to AAR. D) and E) Correlating serum troponin I and IL-6 levels of UNC5B+/− and WT mice (n = 6 per group; *P<0.05; **P<0.01 as indicated) F) Representative TTC stained heart slices of myocardial infarcts (blue/dark = retrograde Evans blue staining; red and white = AAR; white = infarcted tissue).