Table 3.

Prevalence of RET rearrangements in non-small cell lung cancer screening studies

^aAll screened specimens were adenocarcinomas with prior negative testing for alterations in EGFR or ALK.

^bAll screened specimens were adenocarcinomas.

^cAll screened specimens were adenocarcinomas derived from never-smokers.

^dSubset of screened specimens derived from individuals of European ancestry (n = 121) or Asians (n = 405) who were never or limited former smokers.

^eScreened specimens were adenocarcinomas with prior negative testing for alterations in EGFR, ALK, KRAS, BRAF, MEK1, and HER2.

Abbreviations: FISH, fluorescence in situ hybridization; IHC, immunohistochemistry; RT-PCR, reverse transcription polymerase chain reaction.