Table 8. Biomarker associations with patient survival (log-rank test).
95% CI | ||||||||
Marker | Category | N | Failed | % Alive at 12 months | Median (mo) | LL | UL | P-value |
ABCB1 1236C/T (rs1128503) | C | 19 | 10 | 68.4% | 23.6 | 8.2 | . | 0.056 |
T or T/C | 43 | 13 | 81.2% | . | 21.9 | . | ||
ABCB1 2677G/A/T (rs2032582) | G or G/A | 21 | 12 | 71.4% | 17.2 | 11.2 | 25.5 | 0.013 |
T or T/G | 41 | 11 | 80.3% | . | 27.3 | . | ||
ABCB1 3435C/T (rs1045642) | C | 14 | 10 | 71.4% | 14.5 | 4.4 | 25.5 | 0.002 |
T or T/C | 47 | 13 | 78.5% | . | 27.3 | . | ||
MAPT RQ values, 50% cut-off | High | 24 | 6 | 83.1% | . | 23.6 | . | 0.035 |
Low | 24 | 14 | 62.5% | 15.9 | 9.9 | . | ||
TUBB3 RQ values, 75% cut-off | High | 11 | 7 | 54.5% | 12.4 | 4.4 | . | 0.072 |
Low | 35 | 12 | 79.7% | . | 17.2 | . | ||
IHC, PgR | Negative | 19 | 12 | 57.9% | 14.5 | 8.5 | 27.3 | 0.012 |
Positive | 41 | 13 | 80.2% | . | 21.9 | . |
CI, confidence interval; LL, lower limit; N, number; UL, upper limit; “.”, Not reached yet for the median; “.”, Cannot be calculated yet for the UL.