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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: J Immunol. 2013 Jul 1;191(3):1063–1072. doi: 10.4049/jimmunol.1300040

Figure 1. CX3CR1-deficient mice exhibit earlier disease onset and worse EAE disease.

Figure 1

A) Cx3cr1–/– and Cx3cr1+/+ mice were immunized with MOG35-55 peptide and scored daily for neurological signs. B) Days of EAE onset and peak disease. C) Maximum EAE score, N = 14 (Cx3cr1+/+ mice) and N = 15 (Cx3cr1–/– mice). D) Radiation bone marrow chimeras WT → KO (N = 8) and KO → WT (N = 10 ) and respective controls (E) WT → WT (N = 7) and KO → KO (N = 7) were immunized with MOG35-55 peptide and scored daily. ** P < 0.01