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Effects of pretreatment (−30 min) with the inverse agonist of the type-1 cannabinoid (CB1) receptor SR141716 (0, 0.3, 1, and 3 mg/kg, intraperitoneal) on risk-taking behavior and compulsive eating in male Wistar rats (n=44). (A) Time spent in the open, aversive compartment; (B) food intake. Data represent mean (±SEM). Symbols denote significant difference from Chow/Palatable vehicle treated group *p<0.05, ***p<0.001. § denotes a trend (p=0.07).
