Table 1.
Disease codes and rendering physician | Chart Review** | ||||||
---|---|---|---|---|---|---|---|
Number in the population | Number reviewed* | No. of true positives | No. of false positives | Sensitivity (95% CI) | PPV (95% CI) | Estimated no. of true positives in the population | |
PsO without PsA | |||||||
≥ 1 Any Physician | 83,701 | 87 | 65 | 22 | 100*** | 78 | |
≥ 1 Dermatology | 59,671 | 66 | 59 | 7 | 91 (80–96) | 89 (79– 95) | 53,342 |
≥ 2 Dermatology | 39,835 | 43 | 41 | 2 | 63 | 95 | |
≥ 1 Non-Dermatology | 24,022 | 21 | 6 | 15 | 9 | 29 | |
PsA without PsO | |||||||
≥ 1 Any physician | 1,061 | 107 | 57 | 50 | 100*** | 53 | |
≥ 1 Rheumatology | 790 | 73 | 49 | 24 | 86 | 67 | |
≥ 2 Rheumatology | 605 | 54 | 44 | 10 | 77 (64–87) | 81 (68–90) | 493 |
≥ 1 Non-Rheumatology | 271 | 34 | 8 | 26 | 14 | 24 | |
PsO with PsA | |||||||
≥ 1 Any physician | 4,126 | 50 | 32 | 18 | 100*** | 64 (49–77) | |
≥ 1 Dermatology AND ≥1 Rheumatology | 3,427 | 35 | 25 | 10 | 78 (60–90) | 71 (53–85) | 2,448 |
Using the best performing algorithms**** | |||||||
PsO with or without PsA | 63,098 | 101 | 91 | 10 | 88 (89–93) | 90 (83–95) | 55,790 |
PsA with or without PsO | 4,032 | 89 | 71 | 18 | 73 (63–82) | 80 (70–88) | 2,941 |
The best performing algorithms are presented in bold.
A random sample of approximately 0.1% of patients with psoriasis codes alone, 1% of patients with psoriasis and psoriatic arthritis codes, and 10% of patients with psoriatic arthritis codes alone was selected, by assigning random numbers from 0–1.000 and selecting all cases with numbers below 0.001, 0.010, and 0.10, respectively, for validation by chart review.
By definition.
For PsO, ≥1 PsO diagnosis from dermatology. For PsA, ≥2 PsA diagnosis from rheumatology or ≥1 PsA diagnosis from rheumatology AND ≥1 PsO diagnosis from dermatology.