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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: J Immunol. 2013 Jun 24;191(3):1154–1163. doi: 10.4049/jimmunol.1300263

Figure 4. Reduced PC numbers in chimeras lacking BAFF and APRIL in the hematopoetic compartment.

Figure 4

BM cells were collected on d 95 post-immunization from (A) NP-KLH/Alum-immunized chimeras and (B) NP-KLH/α-GC-immunized chimeras. Samples were then assessed by ELISPOT. Each bar shows the mean ± SD number of anti-NP IgG1 secreting cells per million total BM cells. Mean IgG1 titers at day 91 are shown for reference. For B6 and DKO chimeras, 7 and 6 mice per group were used respectively. Statistical significance was assessed using a two-tailed Mann Whitney t-test.