Figure 5. No intrinsic defect in Msr1-deficient B cells.

B cells (7 × 10⁶) isolated from Msr1+/+ and Msr1−/− mice were transferred into separate H-2^b/g7 T cell-deficient hosts that had received 10⁵ KRN⁺ T cells one day prior. Eight days later, the congenically-marked donor B cells were analyzed by flow cytometry. GPI-specific B cells of both genotypes show similar (A) activated CD38⁻GL7⁺ phenotype and (B) Ki67 expression. In control hosts that did not receive KRN⁺ CD4⁺ T cells, too few GPI-specific B cells were recovered for analysis (not shown). The numbers indicate the percentage of cells in each quadrant; results are representative of experiments performed with 3 mice/group.