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. 2013 Jul 23;8(7):e67597. doi: 10.1371/journal.pone.0067597

Table 1. Sequences, Biological activities of HP (2–20) and its analogues.

MIC (µM)
Name Sequence G(+) G(−) Yeast
BS SE SA EC PV ST PA CA TB SC
HP (2–20) AKKVFKRLEKLFSKIQNDK-NH2 1.56 3.13 12.5 6.25 3.13 0.78 12.5 25 12.5–25 25
Anal 1 AKKVFKRLEKLFSKIQNWK-NH2 1.56 0.78 3.13 1.56 1.56 0.39 6.25 12.5 6.25 12.5
Anal 2 AKKVFKRLEKLFSKIWNDK-NH2 1.56 1.56 3.13 1.56 1.56 0.78 6.25 12.5 6.25–12.5 12.5
Anal 3 AKKVFKRLEKLFSKIWNWK-NH2 0.78 0.78 1.56 0.78 1.56 0.39 3.13 6.25 3.13 3.13–6.25
Anal 4 AKKVFKRLEKSFSKIQNDK-NH2 6.25 12.5 >12.5 12.5 6.25 1.56 >12.5 50–100 50 50
Anal 5 AKKVSKRLEKLFSKIQNDK-NH2 3.13 6.25 >12.5 6.25 3.13 3.13 >12.5 100 50 50–100
Anal 3-Pro AKKVFKRLPKLFSKIWNWK-NH2 0.39 0.39 0.39 0.19 0.09 0.09 1.56 3.13 1.56 1.56

G(+), Gram positive bacteria; G(−), Gram negative bacteria; BS, B. substilis; SE, S. epidermides; SA, S. aureus; EC,E. coli; PV, P. vulgalis; ST, S. typhimurium; PA, P. aeruginosa; CA, C. albicans; TB, T. beigellii; SC, S. cerevisiae.