Skip to main content
. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Nat Chem Biol. 2013 Jun 2;9(8):514–520. doi: 10.1038/nchembio.1270

Fig. 3. Functional enhancement of human primary hepatocytes and iHeps.

Fig. 3

(a) Primary screening data of FH1. (b) Primary screening data of FPH1. Control cultures (Ctrl) were treated with empty vehicle (DMSO). All data presented as mean ± s.d. (c) Morphology and colony size of FPH1- and FH1-treated iHeps in 6-well plates 9 days post-initiation-of-treatment. Untreated iHeps are shown for comparison (scale bar = 100 µm). Yellow arrows point to select bile canaliculi. (d) Albumin, CYP3A and AFP staining of iHeps after 9 days of culture (scale bar = 100um). Bar graphs represent quantifications of displayed images.