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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: Am J Ophthalmol. 2013 Apr 17;156(2):362–369. doi: 10.1016/j.ajo.2013.03.005

Table 3.

Clinical Characteristics of Glaucoma Patients Using Glaucoma Medications (n = 157) in a County Hospital Population, by Medication Adherence

Characteristic Medication Adherent Individuals (n=72) Medication Non-Adherent Individuals (n=85) Unadjusted OR for Poor Medication Adherence (95% CI) P value

Years with a glaucoma diagnosis, mean (SD) 6.17 (5.38) 6.52 (6.91) 0.72

Number of glaucoma medications, mean (SD) 2.29 (1.33) 2.04 (1.22) 0.22
 One 25 (34.7) 32 (37.6) 1 [Reference] NA
 Two 19 (26.4) 14 (16.5) 0.58 (0.24–1.36) 0.27
 Three 7 (9.7) 26 (30.6) 2.90 (1.08–7.72) 0.04
 Four or more 21 (29.2) 13 (15.3) 0.48 (0.20–1.15) 0.13

Number of drops per eye per day
 1 to 2 drops 23 (31.9) 25 (29.4) 1 [Reference] NA
 3 to 4 drops 10 (13.9) 8 (9.4) 0.74 (0.25–2.18) 0.78
 5 to 9 drops 20 (27.8) 21 (24.7) 0.97 (0.42–2.22) 1.00
 10 or greater drops 19 (27.1) 31 (36.5) 1.50 (0.67–3.35) 0.41

Monthly out-of-pocket cost of medications (dollars)
 0 25 (34.7) 45 (52.9) 1 [Reference] NA
 0.01 to 5 22 (30.6) 20 (23.5) 0.51 (0.23–1.10) 0.11
 5.01 to 10 6 (8.3) 3 (3.5) 0.28 (0.06–1.20) 0.14
 10.01 to 15 3 (4.2) 2 (2.4) 0.37 (0.06–2.37) 0.36
 15 or greater 16 (22.2) 15 (17.6) 0.52 (0.22–1.22) 0.19

Drug Therapeutic Category
 Prostaglandins (yes vs. no) 51 (80.9) 48 (76.2) 0.85 (0.44–1.63) 0.62
 Alpha-Agonists (yes vs. no) 22 (34.9) 24 (38.1) 1.15 (0.56–2.37) 0.71
 CAI (yes vs. no) 22 (34.9) 21 (33.3) 0.88 (0.43–1.78) 0.72
 Beta Blockers (yes vs. no) 45 (71.4) 42 (66.7) 0.80 (0.38–1.71) 0.56
 Combination (yes vs. no) 1 (1.6) 1 (1.6) 1.0 (0.06–16.35) 1.00

CI = confidence interval

OR = odds ratio

SD = standard deviation

CAI= carbonic anhydrase inhibitor