Table 3.
Clinical Characteristics of Glaucoma Patients Using Glaucoma Medications (n = 157) in a County Hospital Population, by Medication Adherence
| Characteristic | Medication Adherent Individuals (n=72) | Medication Non-Adherent Individuals (n=85) | Unadjusted OR for Poor Medication Adherence (95% CI) | P value |
|---|---|---|---|---|
|
| ||||
| Years with a glaucoma diagnosis, mean (SD) | 6.17 (5.38) | 6.52 (6.91) | 0.72 | |
|
| ||||
| Number of glaucoma medications, mean (SD) | 2.29 (1.33) | 2.04 (1.22) | 0.22 | |
| One | 25 (34.7) | 32 (37.6) | 1 [Reference] | NA |
| Two | 19 (26.4) | 14 (16.5) | 0.58 (0.24–1.36) | 0.27 |
| Three | 7 (9.7) | 26 (30.6) | 2.90 (1.08–7.72) | 0.04 |
| Four or more | 21 (29.2) | 13 (15.3) | 0.48 (0.20–1.15) | 0.13 |
|
| ||||
| Number of drops per eye per day | ||||
| 1 to 2 drops | 23 (31.9) | 25 (29.4) | 1 [Reference] | NA |
| 3 to 4 drops | 10 (13.9) | 8 (9.4) | 0.74 (0.25–2.18) | 0.78 |
| 5 to 9 drops | 20 (27.8) | 21 (24.7) | 0.97 (0.42–2.22) | 1.00 |
| 10 or greater drops | 19 (27.1) | 31 (36.5) | 1.50 (0.67–3.35) | 0.41 |
|
| ||||
| Monthly out-of-pocket cost of medications (dollars) | ||||
| 0 | 25 (34.7) | 45 (52.9) | 1 [Reference] | NA |
| 0.01 to 5 | 22 (30.6) | 20 (23.5) | 0.51 (0.23–1.10) | 0.11 |
| 5.01 to 10 | 6 (8.3) | 3 (3.5) | 0.28 (0.06–1.20) | 0.14 |
| 10.01 to 15 | 3 (4.2) | 2 (2.4) | 0.37 (0.06–2.37) | 0.36 |
| 15 or greater | 16 (22.2) | 15 (17.6) | 0.52 (0.22–1.22) | 0.19 |
|
| ||||
| Drug Therapeutic Category | ||||
| Prostaglandins (yes vs. no) | 51 (80.9) | 48 (76.2) | 0.85 (0.44–1.63) | 0.62 |
| Alpha-Agonists (yes vs. no) | 22 (34.9) | 24 (38.1) | 1.15 (0.56–2.37) | 0.71 |
| CAI (yes vs. no) | 22 (34.9) | 21 (33.3) | 0.88 (0.43–1.78) | 0.72 |
| Beta Blockers (yes vs. no) | 45 (71.4) | 42 (66.7) | 0.80 (0.38–1.71) | 0.56 |
| Combination (yes vs. no) | 1 (1.6) | 1 (1.6) | 1.0 (0.06–16.35) | 1.00 |
CI = confidence interval
OR = odds ratio
SD = standard deviation
CAI= carbonic anhydrase inhibitor