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. 2013 Jul 23;8(7):e68879. doi: 10.1371/journal.pone.0068879

Figure 6. Magnetic activation is not dependent upon the targeting moiety.

Figure 6

Stably transfected HeLa cells expressing chimeric ACP-EGFR, enzymatically modified by biotin CoA and carrying bound Strv-SPIONs. (a) 30 seconds, (b) 180 seconds of magnetization, (c) no magnetization. Green channel, Strv-SPION-biocytin-Alexa546; red channel, phosphorylated-EGFR (pY-EGFR 1068 and GARIG-CY5), overlay of green and red channels. Scale bar, 10 µm.