Table 3. Meta-Module Characteristics.
Meta-Module | # Eigengenes (# probesets) (# unique genes) | Hub Gene (Gene Symbol) | Association with Alcohol Consumption1 (p-value) | mQTL2 Location: Chr (Mb) | mQTL2 LOD Score (p-value) | bQTL overlap |
turquoise | 7 (117) (65) | sterol-C5-desaturase (fungal ERG3, delta-5-desaturase) homolog (S. cerevisae) (Sc5d) | 1.71E-03 | 9 (35.8) | 7.1 (0.028) | Belknap & Atkins (et al., 2001) |
blue | 3 (29) (13) | ribosomal protein S15A Gene (Rps15a) | 9.23E-04 | 7 (124.4) | 5.2 (0.033) | Rodriguez (et al., 1994) |
brown | 2 (16) (13) | LSM12 homolog (S. cerevisiae) (Lsm12) | 1.08E-02 | 11 (100.2) | 3.9 (0.118) | Rodriguez (et al., 1994) |
The size of each meta-module in the eigengene network is reported as number of eigengenes and number of probesets/genes. The hub gene is the highest connected gene of all probesets in the meta-module. 1Unadjusted Fisher's p-value is for association of meta-eigengene and alcohol consumption. 2The mQTL for the meta-module is reported as the location of the highest peak (Chr:Mb).