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. 2013 Jul 23;8(7):e70197. doi: 10.1371/journal.pone.0070197

Figure 4. Humoral immune response observed in IFNAR(−/−) mice vaccinated with DNA/rMVA or rMVA/rMVA expressing VP2/NS1.

Figure 4

Neutralizing antibodies specific of AHSV-4 or AHSV-9 were analyzed in sera of immunized mice by VNT. Neutralization titers at day 15 post-booster treatment in sera of animals immunized with DNA/rMVA (A) or rMVA/rMVA (B) expressing VP2, NS1, or VP2/NS1 are shown. (▴) Non-Immunized, (♦) VP2 immunized, (▪) NS1 immunized, and (•) VP2/NS1 immunized. Means are presented as bars (⁃). Asterisks (*) indicate statistically significant differences (P<0.05) between immunized and non-immunized mice, calculated by signed rank test.