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. 2013 Jul 23;8(7):e70218. doi: 10.1371/journal.pone.0070218

Figure 4. The D466E mutation does not affect the monovalent or divalent cation permeability of the Orco channel.

Figure 4

Representative VUAA1-currents of WT and D466E Orco in extracellular solutions containing 150 mM of the indicated monovalent (A) or divalent cation (C) and 100 µM VUAA1. (B,D) Histograms of the relative permeability of monovalent and divalent cations through WT and D466E Orco complexes relative to Na+. A two-way ANOVA and a Bonferroni post test found no significant differences between WT and D466E (p>0.05, n = 4).