Figure 5. Coiled-coil mutations disrupt CC and NTD dimerization.
Sedimentation velocity data for MBP-CC95–124 (A) and NTD (B) constructs as wild-type (WT) or containing L104D/L108D (2D) or L104A/L108A/M115A/L118A (4A) mutations. Molecular masses corresponding to each peak are reported in Table S1 in the Supporting Information.
