Figure 5. miR-29b and miR-29c are involved in TLR-inhibited Dex-induced pDC apoptosis.

(A, B) Primary pDCs were transfected with control (Ctrl), miR-1, miR-101, miR-148, miR-29b, or miR-29c mimics. Then, cells were stimulated with Dex alone or the combination of Dex and CpG, and pDC apoptosis was analyzed 16 hours post-stimulation. The data are representative of at least 3 independent experiments, each using a different pDC preparation. Data are expressed as the mean ± SD and were analyzed with a 2-tailed Student’s t test. *P<0.05.