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. 2013 Jul 23;8(7):e70005. doi: 10.1371/journal.pone.0070005

Figure 2. Conformational changes observed in variant 1.

Figure 2

A, interactions of S143 in wild-type HA; B, interactions of S143G in variant 1; C, S185 in wild-type HA; D, S185T in variant 1. Amino acids surrounding position 138 are illustrated as sticks; the receptor is depicted as magenta sticks. Interactions with the receptor are essentially the same as the wild-type for variant 1. A displacement of loop 140 can be seen in variant 1, which allows H138 to interact with the main chain of K142 (B). Mutation S185T does not change interactions within the protein (D).