Table 1. BH-forming ability and the physical properties of phospholipids.
Phospholipids | Acyl groups | T m (°C)a | MWb | Total net charge | No. of anion charge | logP c | logD c (pH 5.5) | Hydrogen bond acceptorsc | Hydrogen bonddonorsc | Freely rotating bondsc | Polar surface area (angstrom2)c | Polarizabilityc (×10−24) | BH induction (EC20 values, mM)d |
dilauroyl-PC | 12∶0 | 0 | 621.8 | 0 | 1 | 6.62 | 7.23 | 9 | 1 | 32 | 118.17 | 1 | 6 |
dimyristoyl-PC | 14∶0 | 23 | 677.9 | 0 | 1 | 8.05 | 8.65 | 9 | 1 | 36 | 121 | 1 | 12 |
dipalmitoyl-PC | 16∶0 | 42 | 734.0 | 0 | 1 | 10.09 | 10.69 | 9 | 1 | 40 | 121 | 1 | ND |
distearoyl-PC | 18∶0 | 55 | 790.1 | 0 | 1 | 12.12 | 12.73 | 9 | 1 | 44 | 121 | 1 | ND |
dioleoyl-PC | 18∶1 | −22 | 788.1 | 0 | 1 | 11.96 | 12.57 | 9 | 1 | 42 | 121 | 1 | 5 |
dimyristoyl-PE | 14∶0 | 48 | 635.8 | 0 | 1 | 11.00 | 8.51 | 9 | 3 | 36 | 144.190 | 68.93 | ND |
dipalmitoyl-PE | 16∶0 | 63 | 691.9 | 0 | 1 | 13.70 | 11.20 | 9 | 3 | 40 | 144.19 | 76.276 | ND |
dipalmitoyl-PS | 16∶0 | 51 | 735.9 | −1 | 2 | 13.04 | 9.55 | 11 | 4 | 41 | 181.49 | 78.717 | ND |
Tm: Phase transition temperature was derived from Cevc et al (1993) in Phospholipids Handbook (Cevc, G., ed.), pp. 939–956, Marcel Dekker, New York.
given by supplier.
Values were retrieved from ChemSpider (www.chemspider.com), predicted by Advanced Chemistry Development (ACD/Laboratories) software.
performed by this study.