Table 1.

Biochemical analysis of CHO-K1 cells cultured in Ham’s F12 and RPMI 1640 media, respectively

Biochemical analysis	Ham’s F12	RPMI 1640
Viable cell density (cells/ml)	2.0 × 105–6.18 × 105	2.0 × 105–9.70 × 105
Specific growth rate (d−1)	0.713	0.681
Doubling time, tD (d)	0.972	1.102
Glucose concentration (g/L)	0.06–0.15	0.00–0.08
Glutamine concentration (g/L)	0.01–0.13	0.01–0.41
Lactate concentration (g/L)	0.04–0.22	0.03–0.23
IGF-1 concentration (pg/ml)	28.98–29.87	29.03–31.56
Biomass concentration (g/L)	0.40–1.10	0.10–1.05
qGlc (g/h)	0.18	0.64
qGln (g/h)	0.28	0.30
qLac (g/h)	0.21	0.54
qIGF-1 (pg/h)	0.32	1.37