Fig. 1.

Inhibition of growth of cervical cancer cells by reversine and aspirin a inhibition rate of different drug concentrations on HeLa cells treated with reversine at 10 μmol/L increased compared with mock group, P < 0.05, however, inhibition rate of aspirin group at 10 mmol/L increased significantly, P < 0.05. b reversine (10 μmol/L), aspirin (10 mmol/L) and their combination on U14 cells with different time treatment, inhibition rate of combination group decreased significantly similar to HeLa cells compared with the drug used separately, P < 0.05. c Inhibition rate of the combination of both agents on HeLa and U14 cells at different processing times. d Effect of reversine, aspirin, or their combination on different cervical cancer cell lines (Siha, Caski and C33A) for 48 h; inhibition rate of the combination group significantly increased compared with that when the drug was used separately in different cell lines, P < 0.01