Table 3.

Systemic hyperalgesia.

Parameter	Controls (n = 45)	CFS (n = 39)	GWI (n = 50)
Systemic dolorimetry (kg)	5.5 [4.7–6.3]	2.7 [2.2–3.0]*	3.5 [2.9–4.1]*
Sinus dolorimetry (kg)	2.2 [1.8–2.6]	0.96 [0.80–1.1]*	1.4 [1.2–1.7]*

GWI and CFS subjects had significantly lower systemic and sinus pain thresholds compared to controls.

^*P < 0.0001 vs. controls, ANOVA followed by Tukey's test; mean [95% CI].