Table 1.
Description of demographic data and results of neuropsychological testing in amnestic mild cognitive impairment (aMCI) and healthy age-matched control groups.
| Parameters | Healthy elderly | aMCI | T (df = 40) | p |
|---|---|---|---|---|
| DEMOGRAPHY | ||||
| N | 19 | 23 | ||
| Age (years) | 58.84 (7.41) | 60.30 (9.31) | 0.55 | 0.582 |
| Gender (M/F) | 8/11 | 5/18 | 2.02 | 0.192 |
| Education (years) | 14.74 (2.26) | 13.09 (3.26) | −1.87 | 0.069 |
| Mini-mental state exam | 29.32 (0.82) | 28.91 (1.13) | −1.30 | 0.201 |
| CLINICAL CHARACTERISTICSa | ||||
| Verbal fluency | 29.53 (6.15) | 22.61 (5.70) | −3.78 | 0.001 |
| Boston naming test | 14.74 (0.45) | 14.04 (1.11) | −2.74 | 0.010 |
| Word list learning | 22.58 (2.78) | 18.70 (2.99) | −4.33 | 0.000 |
| Word list recall | 8.79 (1.08) | 5.87 (1.71) | −6.43 | 0.000 |
| Word list: savings | 0.97 (0.09) | 0.78 (0.22) | −3.75 | 0.001 |
| Word list intrusions | 0.16 (0.50) | 0.65 (0.98) | 2.10 | 0.043 |
| Word list recognition | 20.00 (0.00) | 19.61 (0.66) | −2.86 | 0.009 |
| Phonematic fluency | 18.68 (3.43) | 13.65 (5.01) | −3.72 | 0.001 |
| TMT-A | 30.67 (7.81) | 45.39 (20.41) | 2.89 | 0.006 |
| TMT-B | 69.33 (26.42) | 84.83 (35.43) | 1.55 | 0.130 |
| Constructional praxis | 10.95 (0.23) | 10.74 (0.69) | −1.36 | 0.184 |
| Recall of constructional praxis | 10.58 (0.84) | 8.48 (1.93) | −4.72 | 0.000 |
| Constructional praxis: savings | 0.96 (0.06) | 0.79 (0.17) | −4.50 | 0.000 |
Statistical tests of possible group differences (T-values and p-values) are presented.
aMCI, amnestic mild cognitive impairment; denoted are mean values, standard deviations (in brackets), T-, degrees of freedom (df) and p-values.
a
Clinical characteristics are mean raw-scores from subtests of the neuropsychological test battery contained in the Consortium to Establish a Registry for Alzheimer's Disease Plus (CERAD-Plus).
Significant values (p < 0.05) are marked in bold font.