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. Author manuscript; available in PMC: 2013 Jul 24.
Published in final edited form as: J Nat Prod. 2012 Feb 8;75(3):311–335. doi: 10.1021/np200906s

Table 8. Anticancer Drugs from 01.01.81 to 12.31.10 Organized Alphabetically by Generic Name within Source.

generic name trade name year introduced volume page source
Rexin-G 2007 I 346431 B
131I-chTNT 2007 I 393351 B
alemtuzumab Campath 2001 DNP 15 38 B
bevacizumab Avastin 2004 ARMC 40 450 B
catumaxomab Removab 2009 DNP 23 18 B
celmoleukin Celeuk 1992 DNP 06 102 B
cetuximab Erbitux 2003 ARMC 39 346 B
denileukin diftitox Ontak 1999 ARMC 35 338 B
H-101 2005 DNP 19 46 B
ibritumomab Zevalin 2002 ARMC 38 359 B
interferon α-2a Roferon-A 1986 I 204503 B
interferon, γ-1a Biogamma 1992 ARMC 28 332 B
interleukin-2 Proleukin 1989 ARMC 25 314 B
mobenakin Octin 1999 ARMC 35 345 B
BIOMAb
nimotuzumab EFGR 2006 DNP 20 29 B
ofatumumab Arzerra 2009 DNP 23 18 B
panitumumab Vectibix 2006 DNP 20 28 B
pegaspargase Oncaspar 1994 ARMC 30 306 B
rituximab Rituxan 1997 DNP 11 25 B
sipuleucel-T Provenge 2010 I 259673 B
tasonermin Beromun 1999 ARMC 35 349 B
teceleukin Imumace 1992 DNP 06 102 B
tositumomab Bexxar 2003 ARMC 39 364 B
trastuzumab Herceptin 1998 DNP 12 35 B
aclarubicin Aclacin 1981 P090013 N
angiotensin II Delivert 1994 ARMC 30 296 N
arglabin ? 1999 ARMC 35 335 N
masoprocol Actinex 1992 ARMC 28 333 N
paclitaxel Taxol 1993 ARMC 29 342 N
paclitaxel nanoparticles Abraxane 2005 DNP 19 45 N
paclitaxel nanoparticles Nanoxel 2007 I 422122 N
pentostatin Nipent 1992 ARMC 28 334 N
peplomycin Pepleo 1981 P090889 N
romidepsin Istodax 2010 DNP 23 18 N
trabectedin Yondelis 2007 ARMC 43 492 N
solamargines Curaderm 1989 DNP 03 25 NB
alitretinoin Panretin 1999 ARMC 35 333 ND
amrubicin HCl Calsed 2002 ARMC 38 349 ND
belotecan hydrochloride Camtobell 2004 ARMC 40 449 ND
cabazitaxel Jevtana 2010 I 287186 ND
cladribine Leustatin 1993 ARMC 29 335 ND
cytarabine ocfosfate Starsaid 1993 ARMC 29 335 ND
docetaxel Taxotere 1995 ARMC 31 341 ND
elliptinium acetate Celiptium 1983 P091123 ND
epirubicin HCI Farmorubicin 1984 ARMC 20 318 ND
eribulin Halaven 2010 I 287199 ND
etoposide phosphate Etopophos 1996 DNP 10 13 ND
exemestane Aromasin 1999 DNP 13 46 ND
formestane Lentaron 1993 ARMC 29 337 ND
fulvestrant Faslodex 2002 ARMC 38 357 ND
gemtuzumab
ozogamicin Mylotarg 2000 DNP 14 23 ND
hexyl aminolevulinate Hexvix 2004 I 300211 ND
idarubicin hydrochloride Zavedos 1990 ARMC 26 303 ND
irinotecan hydrochloride Campto 1994 ARMC 30 301 ND
ixabepilone Ixempra 2007 ARMC 43 473 ND
mifamurtide Junovan 2010 DNP 23 18 ND
miltefosine Miltex 1993 ARMC 29 340 ND
pirarubicin Pinorubicin 1988 ARMC 24 309 ND
pralatrexate Folotyn 2009 DNP 23 18 ND
talaporfin sodium Laserphyrin 2004 ARMC 40 469 ND
temsirolimus Toricel 2007 ARMC 43 490 ND
topotecan HCl Hycamptin 1996 ARMC 32 320 ND
triptorelin Decapeptyl 1986 I 090485 ND
valrubicin Valstar 1999 ARMC 35 350 ND
vapreotide acetate Docrised 2004 I 135014 ND
vinflunine Javlor 2010 I 219585 ND
vinorelbine Navelbine 1989 ARMC 25 320 ND
zinostatin stimalamer Smancs 1994 ARMC 30 313 ND
aminoglutethimide Cytadren 1981 I 070408 S
amsacrine Amsakrin 1987 ARMC 23 327 S
arsenic trioxide Trisenox 2000 DNP 14 23 S
bisantrene hydrochloride Zantrene 1990 ARMC 26 300 S
carboplatin Paraplatin 1986 ARMC 22 318 S
flutamide Drogenil 1983 ARMC 19 318 S
fotemustine Muphoran 1989 ARMC 25 313 S
heptaplatin/SK-2053R Sunpla 1999 ARMC 35 348 S
lobaplatin Lobaplatin 1998 DNP 12 35 S
lonidamine Doridamina 1987 ARMC 23 337 S
miriplatin hydrate Miripla 2010 DNP 23 17 S
nedaplatin Aqupla 1995 ARMC 31 347 S
nilutamide Anadron 1987 ARMC 23 338 S
oxaliplatin Eloxatin 1996 ARMC 32 313 S
plerixafor hydrochloride Mozobil 2009 DNP 22 17 S
porfimer sodium Photofrin 1993 ARMC 29 343 S
ranimustine Cymerine 1987 ARMC 23 341 S
sobuzoxane Parazolin 1994 ARMC 30 310 S
sorafenib Nexavar 2005 DNP 19 45 S
anastrozole Arimidex 1995 ARMC 31 338 S/NM
bicalutamide Casodex 1995 ARMC 31 338 S/NM
bortezomib Velcade 2003 ARMC 39 345 S/NM
camostat mesylate Foipan 1985 ARMC 21 325 S/NM
dasatinib Sprycel 2006 DNP 20 27 S/NM
erlotinib hydrochloride Tarceva 2004 ARMC 40 454 S/NM
fadrozole HCl Afema 1995 ARMC 31 342 S/NM
gefitinib Iressa 2002 ARMC 38 358 S/NM
imatinib mesilate Gleevec 2001 DNP 15 38 S/NM
lapatinib ditosylate Tykerb 2007 ARMC 43 475 S/NM
letrazole Femara 1996 ARMC 32 311 S/NM
nilotinib hydrochloride Tasigna 2007 ARMC 43 480 S/NM
pazopanib Votrient 2009 DNP 23 18 S/NM
sunitinib malate Sutent 2006 DNP 20 27 S/NM
temoporfin Foscan 2002 I 158118 S/NM
toremifene Fareston 1989 ARMC 25 319 S/NM
zoledronic acid Zometa 2000 DNP 14 24 S
azacytidine Vidaza 2004 ARMC 40 447 S*
capecitabine Xeloda 1998 ARMC 34 319 S*
carmofur Mifurol 1981 I 091100 S*
clofarabine Clolar 2005 DNP 19 44 S*
decitabine Dacogen 2006 DNP 20 27 S*
doxifluridine Furtulon 1987 ARMC 23 332 S*
enocitabine Sunrabin 1983 ARMC 19 318 S*
fludarabine phosphate Fludara 1991 ARMC 27 327 S*
gemcitabine HCl Gemzar 1995 ARMC 31 344 S*
mitoxantrone HCI Novantrone 1984 ARMC 20 321 S*
nelarabine Arranon 2006 ARMC 42 528 S*
abarelix Plenaxis 2004 ARMC 40 446 S*/NM
bexarotene Targretine 2000 DNP 14 23 S*/NM
degarelix Firmagon 2009 DNP 22 16 S*/NM
pemetrexed disodium Alimta 2004 ARMC 40 463 S*/NM
raltitrexed Tomudex 1996 ARMC 32 315 S*/NM
tamibarotene Amnoid 2005 DNP 19 45 S*/NM
temozolomide Temodal 1999 ARMC 35 350 S*/NM
vorinostat Zolinza 2006 DNP 20 27 S*/NM
Cervarix 2007 I 309201 V
autologous tumor cell-BCG OncoVAX 2008 DNP 22 17 V
bcg live TheraCys 1990 DNP 04 104 V
melanoma theraccine Melacine 2001 DNP 15 38 V
vitespen Oncophage 2008 DNP 22 17 V