Table 1. Distribution patterns of characteristics among cases with and without tissue and data for ER/PR/HER-2 status, CASH study.
Factor | Cases excluded from analysis (n = 2,627) | Cases in analysis (n = 890) | p-Value | ||
---|---|---|---|---|---|
|
|
||||
N | % | N | % | ||
Agea | |||||
<35 | 266 | 10.1 | 85 | 9.6 | |
35–39 | 342 | 13.0 | 110 | 12.4 | |
40–44 | 467 | 17.8 | 159 | 17.9 | |
45–49 | 676 | 25.7 | 204 | 22.9 | |
50–54 | 763 | 29.0 | 294 | 33.0 | |
55+ | 113 | 4.3 | 38 | 4.3 | N/C |
Missing | 0 | 0 | |||
Racea | |||||
White | 2,233 | 85.0 | 810 | 91.0 | |
Black | 296 | 11.3 | 48 | 5.4 | |
Other | 98 | 3.7 | 32 | 3.6 | N/C |
Missing | 0 | 0 | |||
Age at menarche | |||||
<12 | 651 | 33.6 | 214 | 35.7 | |
12 | 664 | 36.9 | 241 | 34.6 | |
13 | 729 | 29.1 | 234 | 29.4 | |
14+ | 575 | 0.4 | 199 | 0.3 | 0.67 |
Missing | 8 | 2 | |||
Parity | |||||
0 | 447 | 17.2 | 129 | 14.5 | |
1 | 334 | 12.8 | 95 | 10.7 | |
2 | 685 | 26.3 | 268 | 30.2 | |
3 | 563 | 21.6 | 191 | 21.5 | |
4+ | 577 | 22.1 | 204 | 23.0 | 0.059 |
Missing | 21 | 3 | |||
Age at first birth (among parous) | |||||
<20 | 439 | 20.7 | 148 | 19.8 | |
20–22 | 626 | 29.6 | 219 | 29.2 | |
23–24 | 377 | 17.8 | 147 | 19.6 | |
25+ | 675 | 31.9 | 235 | 31.4 | 0.72 |
Missing | 510 | 141 | |||
Months of breastfeeding (among parous) | |||||
0 | 1,158 | 54.1 | 410 | 54.4 | |
1–5 | 526 | 24.6 | 211 | 28.0 | |
6+ | 457 | 21.3 | 132 | 17.5 | 0.037 |
Missing | 486 | 137 | |||
Infertility problems | |||||
No | 2,018 | 81.3 | 690 | 81.2 | |
Yes | 465 | 18.7 | 160 | 18.8 | 0.95 |
Missing | 144 | 40 | |||
Duration (months) of OC useb | |||||
0 | 1,167 | 44.6 | 409 | 46.2 | |
1–5 | 131 | 5.0 | 36 | 4.1 | |
6–11 | 562 | 21.5 | 176 | 19.9 | |
12–60 | 544 | 20.8 | 193 | 21.8 | |
>60 | 212 | 8.1 | 72 | 8.1 | 0.61 |
Missing | 11 | 4 | |||
Menopausal status (abbreviated) | |||||
Premenopausal | 1,184 | 46.5 | 392 | 45.9 | |
Perimenopausal | 494 | 19.4 | 153 | 17.9 | |
Postmenopausal | 867 | 34.1 | 309 | 36.2 | 0.44 |
Missing | 82 | 36 | |||
Benign breast disease | |||||
No | 2,137 | 90.2 | 736 | 92.9 | |
Yes | 442 | 9.8 | 143 | 7.1 | 0.55 |
Missing | 48 | 11 | |||
Family history of breast cancer | |||||
No | 2,168 | 87.6 | 720 | 87.7 | |
Yes | 307 | 12.4 | 101 | 12.3 | 0.94 |
Missing | 152 | 69 | |||
BMI (kg/m2) at reference (WHO categories) | |||||
≤18.5 | 114 | 4.4 | 33 | 3.7 | |
18.6–25.0 | 1,863 | 71.3 | 615 | 69.4 | |
25.1–30.0 | 460 | 17.6 | 174 | 19.6 | |
>30.0 | 175 | 6.7 | 64 | 7.2 | 0.43 |
Missing | 15 | 4 | |||
Breast cancer tumor stage | |||||
0 | 22 | 2.5 | |||
I | 396 | 44.5 | |||
II | 430 | 48.3 | |||
III | 0 | 0.0 | |||
IV | 31 | 3.5 | |||
Missing | 11 | 1.2 | |||
Breast cancer tumor histology | |||||
Ductal carcinoma in situ | 32 | 3.6 | |||
Invasive ductal carcinoma | 642 | 72.1 | |||
Lobular carcinoma in situ | 51 | 5.7 | |||
Invasive lobular carcinoma | 1 | 0.1 | |||
Medullary carcinoma | 59 | 6.6 | |||
Other | 100 | 11.2 | |||
Missing | 5 | 0.6 |
Matching factors thus p-values were not calculated (N/C)
Included women who are currently pregnant, recently pregnant, or currently breast feeding