Table 1.
Genome-wide replication profiles
| Species | Cell type | Cell line | References |
|---|---|---|---|
| Homo sapiens | hESC | H1 | Desprat et al. 2009; Ryba et al. 2011 |
| H7 | Ryba et al. 2010 | ||
| H9 | Ryba et al. 2010 | ||
| BG01 | Ryba et al. 2010 | ||
| BG02 | Hansen et al. 2010; Ryba et al. 2010 | ||
| hiPSC | iPSC4 | Ryba et al. 2010 | |
| iPSC5 | Ryba et al. 2010 | ||
| Definitive endoderm | BG02-derived | Ryba et al. 2011 | |
| Mesendoderm | BG02-derived | Ryba et al. 2011 | |
| Mesoderm | BG02-derived | Ryba et al. 2011 | |
| Smooth muscle | BG02-derived | Ryba et al. 2011 | |
| Neural precursors | BG01-derived | Ryba et al. 2010 | |
| Myoblast | 7 individuals | Pope et al. 2011 | |
| Lymphoblastoid | CO2O2 (male) | Ryba et al. 2010 | |
| GM06990 (female) | Hansen et al. 2010; Ryba et al. 2011 | ||
| TL010 | Hansen et al. 2010 | ||
| HO287 (male) | Hansen et al. 2010 | ||
| MOLT-4 | Yaffe et al. 2010 | ||
| Fibroblast | IMR90 | Pope et al. 2011 | |
| BJ | Hansen et al. 2010 | ||
| FFT | Yaffe et al. 2010 | ||
| HeLa | Chen et al. 2010 | ||
| Erythroid | K562 | Hansen et al. 2010 | |
| CD4+-derived basophilic erythroblasts | Desprat et al. 2009 | ||
| Mus musculus | mESC | D3 | Hiratani et al. 2008 |
| 46C | Hiratani et al. 2008 | ||
| TT2 | Hiratani et al. 2008 | ||
| TT2 flox G9a ESC: mock and OHT | Yokochi et al. 2009 | ||
| miPSC | iPS | Hiratani et al. 2008 | |
| iPSC1D4 | Hiratani et al. 2010 | ||
| iPSC2D4 | Hiratani et al. 2010 | ||
| pmiPSC | piPSC1A2 | Hiratani et al. 2010 | |
| piPSC1B3 | Hiratani et al. 2010 | ||
| piPSC1V3 | Hiratani et al. 2010 | ||
| Early primitive ectoderm | D3-derived as embryoid bodies | Hiratani et al. 2010 | |
| Early primitive ectoderm | D3-derived as monolayer | Hiratani et al. 2010 | |
| Definitive ectoderm | D3-derived as embryoid bodies | Hiratani et al. 2010 | |
| Neural precursors | D3-derived as embryoid bodies | Hiratani et al. 2008 | |
| 46C-derived as monolayer | Hiratani et al. 2008 | ||
| TT2-derived as monolayer | Hiratani et al. 2008 | ||
| TT2 flox G9a-derived: mock and OHT | Yokochi et al. 2009 | ||
| Endoderm | GscSox17-EB5-derived | Hiratani et al. 2010 | |
| Mesoderm | GscSox17-EB5-derived | Hiratani et al. 2010 | |
| mEpiSC | EpiSC5 | Hiratani et al. 2010 | |
| EpiSC7 (female) | Hiratani et al. 2010 | ||
| Lymphoblastoid | L1210 | Farkash-Amar et al. 2008; Hiratani et al. 2010 | |
| Fibroblast | C127 mammary | Lu et al. 2010 | |
| MEF male and female | Hiratani et al. 2010; Yaffe et al. 2010 | ||
| Myoblast | J185a | Hiratani et al. 2010 | |
| Drosophila melanogaster | Wing imaginal disc | Cl8 | Schwaiger et al. 2009 |
| Embryonic | Kc | Schwaiger et al. 2009; Eaton et al. 2011 | |
| Kc HP1 knockdown | Schwaiger et al. 2010 | ||
| S2 | Eaton et al. 2011 | ||
| Neuronal | Bg3 | Eaton et al. 2011 | |
| Chicken | Lymphoid | DT40 | Hassan-Zadeh et al. 2012 |
| Arabidopsis thalania | Col-0 (chromosome 4 only) | Lee et al. 2010 | |
| Saccharomyces cerevisiae | wt | Raghuraman et al. 2001 | |
| wt | Yabuki et al. 2002 | ||
| wt | Feng et al. 2006 | ||
| rad35Δ | Feng et al. 2006 | ||
| wt | Alvino et al. 2007 | ||
| wt + HU | Alvino et al. 2007 | ||
| wt | McCune et al. 2008 | ||
| clb5Δ | McCune et al. 2008 | ||
| clb5Δ clb6Δ | McCune et al. 2008 | ||
| wt | Knott et al. 2009 | ||
| rpd3Δ | Knott et al. 2009 | ||
| eaf3Δ (Rpd3S) | Knott et al. 2009 | ||
| set2Δ (Rpd3S) | Knott et al. 2009 | ||
| rco1Δ (Rpd3S) | Knott et al. 2009 | ||
| dep1Δ (Rpd3L) | Knott et al. 2009 | ||
| cti6Δ (Rpd3L) | Knott et al. 2009 | ||
| rpd3Δ set2Δ | Knott et al. 2009 | ||
| rpd3Δ cti6Δ | Knott et al. 2009 | ||
| rpd3Δ eaf3Δ | Knott et al. 2009 | ||
| cti6Δ eaf3Δ | Knott et al. 2009 | ||
| dep1Δ eaf3Δ | Knott et al. 2009 | ||
| rco1Δ eaf3Δ | Knott et al. 2009 | ||
| eaf3Δ set2Δ | Knott et al. 2009 | ||
| wt | Crabbe et al. 2010 | ||
| rad9 | Crabbe et al. 2010 | ||
| rev3 rad30 | Crabbe et al. 2010 | ||
| eco1 | Crabbe et al. 2010 | ||
| ctf4 | Crabbe et al. 2010 | ||
| ddc1 | Crabbe et al. 2010 | ||
| rad24 | Crabbe et al. 2010 | ||
| pol2-12 | Crabbe et al. 2010 | ||
| elg1 | Crabbe et al. 2010 | ||
| tof1 | Crabbe et al. 2010 | ||
| mrc1AQ | Crabbe et al. 2010 | ||
| mrc1AQ rad9 | Crabbe et al. 2010 | ||
| ctf8 | Crabbe et al. 2010 | ||
| ctf18 | Crabbe et al. 2010 | ||
| mrc1 | Crabbe et al. 2010 | ||
| ddc1 | Crabbe et al. 2010 | ||
| ctf18 rad9 | Crabbe et al. 2010 | ||
| mec1-100 | Crabbe et al. 2010 | ||
| mec1-100 | Crabbe et al. 2010 | ||
| mec1-100 | Crabbe et al. 2010 | ||
| mec1-100 | Crabbe et al. 2010 | ||
| rad53 | Crabbe et al. 2010 | ||
| wt | Lian et al. 2011 | ||
| yku70Δ | Lian et al. 2011 | ||
| wt | Koren et al. 2010 | ||
| sic1Δ | Koren et al. 2010 | ||
| dia2Δ | Koren et al. 2010 | ||
| clb5Δ | Koren et al. 2010 | ||
| mrc1Δ | Koren et al. 2010 | ||
| rrm3Δ | Koren et al. 2010 | ||
| dpb3Δ | Koren et al. 2010 | ||
| dpb4Δ | Koren et al. 2010 | ||
| rnr1Δ | Koren et al. 2010 | ||
| rad27Δ | Koren et al. 2010 | ||
| ura7Δ | Koren et al. 2010 | ||
| tda3Δ | Koren et al. 2010 | ||
| met7Δ | Koren et al. 2010 | ||
| gln3Δ | Koren et al. 2010 | ||
| arg2Δ | Koren et al. 2010 | ||
| wt | Tanaka et al. 2011 | ||
| Overexpression of Sld3, Sld7, and Cdc45 | Tanaka et al. 2011 | ||
| Overexpression of Dbf4 | Tanaka et al. 2011 | ||
| Overexpression of Cdc7 and Dbf4 | Tanaka et al. 2011 | ||
| wt | Knott et al. 2012 | ||
| fkh1Δ | Knott et al. 2012 | ||
| fkh2Δ | Knott et al. 2012 | ||
| fkh1Δ fkh2Δ | Knott et al. 2012 | ||
| Schizosaccharomyces pombe |
wt |
Heichinger et al. 2006 |
|
| wt | Feng et al. 2006 | ||
| wt | Hayashi et al. 2007 | ||
| wt | Eshaghi et al. 2007 | ||
| wt | Mickle et al. 2007b | ||
| wt | Mickle et al. 2007a | ||
| wt | Kumar and Huberman 2009 | ||
| wt | Wu and Nurse 2009 | ||
| wt | Hayano et al. 2011 | ||
| wt | Hayano et al. 2011 | ||
| wt | Xu et al. 2012 |
hESC, human embryonic stem cells; hiPSC, human-induced pluripotent stem cells; mESC, mouse embryonic stem cells; OHT, 4-hydoxytamoxifen; miPSC, mouse-induced pluripotent stem cells; pmiPSC, partially reprogrammed mouse-induced pluripotent stem cells; mEpiSC, mouse epiblast-derived stem cells; wt, wild type; HU, hydroxyurea.