Figure 6. Expression of CT-X antigens in the intratubular component of spermatocytic seminoma and adjacent non-neoplastic seminiferous tubules. All intratubular tumor cells showed diffuse expression of CT-X antigens, as pure nuclear antigens (CT45 and SAGE1), predominantly cytoplasmic antigens (CT7 and NY-ESO-1), or mixed nuclear and cytoplasmic antigens (MAGE-A and GAGE). Adjacent non-neoplastic tubules showed strong staining of the spermatogonia, with variable staining of the more mature forms. (Magnification, 400X).