Table 3.

Arabidopsis thaliana members of the CIA and ISC export machineries.

Protein names	AGI numbers	Phenotype(s) of mutant plants	Reference(s)
NAR1/GOLLUM	At4g16440	Embryo lethal	Cavazza et al., 2008; Luo et al., 2012
CIA1	At2g26060	Embryo lethal	Luo et al., 2012
NBP35	At5g50960	Embryo lethal	Bych et al., 2008b
AE7/ MIP18/CIA2	At1g68310	Strong allele is embryo lethal, weak alleles are viable but exhibit highly accumulated DNA damage and cell cycle arrest	Yuan et al., 2010; Luo et al., 2012
MET18/MMS19	At5g48120	No phenotype under standard growth conditions	Luo et al., 2012
DRE2/CIAPIN	At5g18400	Embryo lethal	Bernard et al., 2013
TAH18/ATR3	At3g02280	Embryo lethal	Varadarajan et al., 2010
ATM3/ABCB7	At5g58270	Defects in root growth, chlorophyll content and seedling establishment	Kushnir et al., 2001; Kim et al., 2006; Bernard et al., 2009
ERV1/ALR	At1g49880	Embryo lethal	Carrie et al., 2010

Except ATM3 and ERV1 which code for the two protein components of the ISC machinery, all other genes code for proteins of the CIA machinery. Yeast and human names have been indicated. ATM1 (At4g28630), ATM2 (At4g28620), AE7.2/AEL1 (At3g50845) and AE7.3/AEL2 (At3g09380) genes have not been listed here considering that they are not able to complement atm3 and ae7 mutants. There are putative additional CIA1 (At4g32990) and DRE2 genes (At5g18362) but, from EST or transcriptomic data, there is no evidence that they are expressed.