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miR-320c induced gemcitabine resistance in MiaPaCa2 cells. (A, B) Real-time qRT-PCR confirmed overexpression (MiaPaCa2-P transfected with pre-miR-320c) and suppression (MiaPaCa2-RG1 transfected with anti-miR-320c) of miR-320c for >72 h. (C, D) MTT assay showed significant changes in resistance to gemcitabine by gain-of-function of miR-320c in MiaPaCa2-P and loss-of-function in MiaPaCa2-RG1. Data are mean±s.d. of triplicate independent experiments. *P<0.05.
