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. 2013 Jun 25;109(2):482–492. doi: 10.1038/bjc.2013.321

Table 1. Comparison of clinicopathologic features between Ron+ and Ron− HNSCCs.

  Ron+ HNSCCs, n=83 (65.4%) Ron− HNSCCs, n=44 (34.6%) P-value
Age (years)
61.1±11.8
55.7±9.4
<0.01
Sex
Female 18 (21.7%) 10 (22.7%)  
Male
65 (78.3%)
34 (77.3%)
NS
Tumour sites
Oropharynx 68 (81.9%) 29 (65.9%)  
Larynx
15 (18.1%)
15 (34.1%)
0.05
Smoking (pack years)
37.8±36.2
36.2±29.7
NS
Differentiation
Missing 2 (2.4%) 0  
Well 12 (14.5%) 6 (13.6%)  
Moderate 46 (55.4%) 31 (70.5%)  
Poor
23 (27.7%)
7 (15.9%)
NS
Perineural invasion
Missing 22 (26.5%) 14 (31.8%)  
Yes 35 (42.2%) 18 (40.9%)  
No
26 (31.3%)
12 (27.3%)
NS
Lymphovascular invasion
Missing 15 (18.1%) 2 (4.5%)  
Yes 23 (27.7%) 19 (43.2%)  
No
45 (54.2%)
23 (52.3%)
NS
Tumour size (log cm3)
3.23±1.25
2.97±1.35
NS
T stage
Tx 1 (1.2%) 1 (2.3%)  
Tis/T1/T2 23 (27.7%) 15 (34.1%)  
T3 /T4
59 (71.1%)
28 (63.6%)
NS
N stage
Nx 11 (13.2%) 5 (11.4%)  
N0/N1 40 (48.2%) 22 (50%)  
N2/N3
32 (38.6%)
17 (38.6%)
NS
Overall stage
Missing 9 (10.8%) 5 (11.4%)  
1–2 9 (10.8%) 5 (11.4%)  
3–4
65 (78.4%)
34 (77.2%)
NS
Recurrence 7 (8.4%) 4 (9.1%)  

Abbreviations: HNSCC=head and neck squamous cell carcinoma; NS=not significant.