Table 1. LINE-1 methylation level and clinical or epidemiological features of liver metastases from colorectal cancer.
| Clinical or epidemiological features | N (%)a | LINE-1 methylation levelmean (%) | P-value |
|---|---|---|---|
| All cases |
42 |
67.3 |
|
|
Age | |||
| <65 | 25 (60.0%) | 67.2 | 0.798 |
| ⩽65 |
17(40.0%) |
67.5 |
|
|
Sex | |||
| Male | 26 (61.9%) | 67.7 | 0.786 |
| Female |
16 (38.1%) |
66.6 |
|
|
Year of operation | |||
| 2001–2006 | 24 (57.1%) | 67.8 | 0.657 |
| 2007–2012 |
18 (42.9%) |
66.6 |
|
|
Tumour size (mm) | |||
| 35< | 21 (50.0%) | 67.0 | 0.841 |
| ⩾35 |
21 (50.0%) |
67.6 |
|
|
Detection of metastases | |||
| Synchronous | 15 (35.7%) | 64.7 | 0.217 |
| Metachronous |
27 (64.3%) |
68.8 |
|
|
Postoperative chemotherapy | |||
| Yes | 32 (76.2%) | 68.9 | 0.079 |
| No |
10 (23.8%) |
62.4 |
|
|
Stage | |||
| I | 4 (9.5%) | 70.7 | 0.161 |
| II | 11 (26.2%) | 72.7 | |
| III | 11 (26.2%) | 65.0 | |
| IV | 16 (38.1%) | 64.4 | |
There is no significant relation between LINE-1 and any of the clinical or epidemiological features examined.
a
% indicates the proportion of cases with a specific clinical or epidemiological feature.