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. Author manuscript; available in PMC: 2014 Aug 29.
Published in final edited form as: Neuroscience. 2013 Apr 25;246:382–390. doi: 10.1016/j.neuroscience.2013.04.037

Figure 2. SB treatment improves rotenone-induced locomotor impairment.

Figure 2

In the absence of rotenone, 10 mM SB treatment does not change negative geotactic response in wild type flies. Exposure to 125 μM rotenone for 3 days caused a robust decrease in negative geotactic response as compared to vehicle only. In the presence of rotenone, 10 mM SB treatment for 3 days improved negative geotactic response and showed a significant increase in the odds of flies reaching the top of the apparatus. Columns=average percentage of flies reaching the top section of the apparatus after 1 min; error bars=standard error; OR=odds ratio of mobility to top section as compared to without SB control for the same rotenone dose; *** p<0.001 for odds of survival; n=3–8 biological replicates set in at least duplicates.