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. Author manuscript; available in PMC: 2013 Nov 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2012 Jul 25;21(11):2006–2013. doi: 10.1158/1055-9965.EPI-12-0418

Table 2.

Alcohol consumption at follow-up and breast cancer risk overall and by HT use in the CTS cohort.

Alcohol (g/d) Person-years Cases RRa 95% CI RRb 95% CI
All women
 non-drinker 56,085 233 1.0 1.0c
 <20 71,632 293 1.01 0.85–1.20 1.01 0.85–1.20
 ≥20 26,144 134 1.24 1.00–1.53 1.26 1.02–1.56
Never used HT
 non-drinker 14,267 50 1.0 1.0
 <20 15,858 40 0.77 0.50–1.16 0.78 0.51–1.18
 ≥20 5,160 25 1.47 0.91–2.38 1.52 0.94–2.47
Past HT use
 non-drinker 28,379 117 1.02 0.73–1.42 1.05 0.75–1.47
 <20 36,889 145 0.98 0.71–1.36 1.03 0.74–1.43
 ≥20 13,826 58 1.04 0.71–1.52 1.10 0.75–1.62
  Stopped HT ≥5 yrsd
   non-drinker 15,748 65 0.99 0.68–1.44 1.02 0.70–1.48
   <20 17,859 82 1.11 0.78–1.59 1.16 0.81–1.66
   ≥20 6,814 30 1.05 0.66–1.66 1.11 0.70–1.76
  Stopped HT 34 yrsd
   non-drinker 6,888 31 1.15 0.73–1.81 1.20 0.76–1.89
   <20 10,843 36 0.87 0.57–1.34 0.91 0.59–1.40
   ≥20 4,007 15 0.97 0.54–1.74 1.04 0.58–1.86
  Stopped HT <3 yrsd
   non-drinker 5,186 17 0.82 0.47–1.43 0.84 0.49–1.47
   <20 7,435 26 0.87 0.54–1.41 0.93 0.57–1.49
   ≥20 2,748 11 1.00 0.52–1.92 1.06 0.55–2.04
Current HT use
 non-drinker 11,588 58 1.28 0.87–1.88 1.34 0.91–1.97
 <20 17,031 98 1.50 1.06–2.12 1.60 1.13–2.26
 ≥20 6,486 50 1.96 1.32–2.91 2.11 1.41–3.15
a

Age was the time-scale and analyses were stratified by age at follow-up.

b

Adjusted for age at first full-term pregnancy/nulliparity, family history of breast cancer in a first degree relative, body mass index, and long-term physical inactivity; age was the time-scale and analyses were stratified by age at follow-up.

c

Additionally adjusted for HT use.

d

Time period is relative to completion of the 10-year follow-up questionnaire.