Table 2.
Alcohol (g/d) | Person-years | Cases | RRa | 95% CI | RRb | 95% CI |
---|---|---|---|---|---|---|
All women | ||||||
non-drinker | 56,085 | 233 | 1.0 | 1.0c | ||
<20 | 71,632 | 293 | 1.01 | 0.85–1.20 | 1.01 | 0.85–1.20 |
≥20 | 26,144 | 134 | 1.24 | 1.00–1.53 | 1.26 | 1.02–1.56 |
Never used HT | ||||||
non-drinker | 14,267 | 50 | 1.0 | 1.0 | ||
<20 | 15,858 | 40 | 0.77 | 0.50–1.16 | 0.78 | 0.51–1.18 |
≥20 | 5,160 | 25 | 1.47 | 0.91–2.38 | 1.52 | 0.94–2.47 |
Past HT use | ||||||
non-drinker | 28,379 | 117 | 1.02 | 0.73–1.42 | 1.05 | 0.75–1.47 |
<20 | 36,889 | 145 | 0.98 | 0.71–1.36 | 1.03 | 0.74–1.43 |
≥20 | 13,826 | 58 | 1.04 | 0.71–1.52 | 1.10 | 0.75–1.62 |
Stopped HT ≥5 yrsd | ||||||
non-drinker | 15,748 | 65 | 0.99 | 0.68–1.44 | 1.02 | 0.70–1.48 |
<20 | 17,859 | 82 | 1.11 | 0.78–1.59 | 1.16 | 0.81–1.66 |
≥20 | 6,814 | 30 | 1.05 | 0.66–1.66 | 1.11 | 0.70–1.76 |
Stopped HT 3–4 yrsd | ||||||
non-drinker | 6,888 | 31 | 1.15 | 0.73–1.81 | 1.20 | 0.76–1.89 |
<20 | 10,843 | 36 | 0.87 | 0.57–1.34 | 0.91 | 0.59–1.40 |
≥20 | 4,007 | 15 | 0.97 | 0.54–1.74 | 1.04 | 0.58–1.86 |
Stopped HT <3 yrsd | ||||||
non-drinker | 5,186 | 17 | 0.82 | 0.47–1.43 | 0.84 | 0.49–1.47 |
<20 | 7,435 | 26 | 0.87 | 0.54–1.41 | 0.93 | 0.57–1.49 |
≥20 | 2,748 | 11 | 1.00 | 0.52–1.92 | 1.06 | 0.55–2.04 |
Current HT use | ||||||
non-drinker | 11,588 | 58 | 1.28 | 0.87–1.88 | 1.34 | 0.91–1.97 |
<20 | 17,031 | 98 | 1.50 | 1.06–2.12 | 1.60 | 1.13–2.26 |
≥20 | 6,486 | 50 | 1.96 | 1.32–2.91 | 2.11 | 1.41–3.15 |
Age was the time-scale and analyses were stratified by age at follow-up.
Adjusted for age at first full-term pregnancy/nulliparity, family history of breast cancer in a first degree relative, body mass index, and long-term physical inactivity; age was the time-scale and analyses were stratified by age at follow-up.
Additionally adjusted for HT use.
Time period is relative to completion of the 10-year follow-up questionnaire.