Table 1.
Differentially expressed genes in trkB.T1 KO versus WT at 1 d after SCI
| Probe set ID | Gene symbol | Gene name | Entrez ID | Chr | logFC | AveExpr | p-value | FDR |
|---|---|---|---|---|---|---|---|---|
| 1435196_at | Ntrk2 | Neurotrophic tyrosine kinase, receptor, type 2 | 18212 | 13 | −6.310548984 | 6.283996342 | 4.04E-10 | 2.28E-06 |
| 1420838_at | Ntrk2 | Neurotrophic tyrosine kinase, receptor, type 2 | 18212 | 13 | −6.111087346 | 7.430315809 | 6.27E-10 | 3.14E-06 |
| 1426817_at | Mki67 | Antigen identified by monoclonal antibody Ki 67 | 17345 | 7 | −3.524221569 | 7.362224422 | 3.99E-08 | 9.99E-05 |
| 1454694_a_at | Top2a | Topoisomerase (DNA) II alpha | 21973 | 11 | −2.884216275 | 7.007219836 | 6.78E-11 | 1.22E-06 |
| 1448627_s_at | Pbk | PDZ binding kinase | 52033 | 14 | −2.716160403 | 7.021488258 | 2.49E-09 | 1.02E-05 |
| 1448226_at | Rrm2 | Ribonucleotide reductase M2 | 20135 | 12 | −2.597777888 | 7.010958985 | 3.35E-10 | 2.28E-06 |
| 1434437_x_at | Rrm2 | Ribonucleotide reductase M2 | 20135 | 12 | −2.413044131 | 8.510323758 | 3.29E-09 | 1.24E-05 |
| 1424278_a_at | Birc5 | Baculoviral IAP repeat-containing 5 | 11799 | 11 | −2.402215946 | 6.501212468 | 4.95E-09 | 1.72E-05 |
| 1438009_at | −2.354901604 | 10.44514503 | 1.08E-10 | 1.22E-06 | ||||
| 1452242_at | Cep55 | Centrosomal protein 55 | 74107 | 19 | −2.324549301 | 5.951673121 | 1.65E-10 | 1.49E-06 |
| 1417910_at | Ccna2 | Cyclin A2 | 12428 | 3 | −2.299017545 | 6.317339253 | 3.79E-10 | 2.28E-06 |
| 1416802_a_at | Cdca5 | Cell division cycle associated 5 | 67849 | 19 | −2.25450247 | 5.071325741 | 1.04E-10 | 1.22E-06 |
| 1424046_at | Bub1 | Budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) | 12235 | 2 | −2.227622933 | 4.833076836 | 2.89E-08 | 7.68E-05 |
| 1448314_at | Cdk1 | Cyclin-dependent kinase 1 | 12534 | 10 | −2.19726873 | 6.307649069 | 4.13E-11 | 1.22E-06 |
| 1419153_at | 2810417H13Rik | RIKEN cdna 2810417H13 gene | 68026 | 9 | −2.074215817 | 7.573282138 | 5.82E-08 | 0.000131177 |
| 1436847_s_at | Cdca8 | Cell division cycle associated 8 | 52276 | 4 | −2.009899382 | 6.032914831 | 2.09E-08 | 5.90E-05 |
| 1428481_s_at | Cdca8 | Cell division cycle associated 8 | 52276 | 4 | −1.976062259 | 5.200284503 | 1.02E-08 | 3.30E-05 |
| 1417821_at | D17H6S56E-5 | DNA segment, Chr 17, human D6S56E 5 | 110956 | 17 | −1.950723814 | 5.7321697 | 2.22E-09 | 1.00E-05 |
| 1417911_at | Ccna2 | Cyclin A2 | 12428 | 3 | −1.764308783 | 4.797649583 | 1.05E-07 | 0.000214275 |
| 1424118_a_at | Spc25 | SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) | 66442 | 2 | −1.697970249 | 5.60872748 | 4.69E-07 | 0.000729463 |
| 1416299_at | Shcbp1 | Shc SH2-domain binding protein 1 | 20419 | 8 | −1.676308459 | 6.751182549 | 1.32E-07 | 0.00025896 |
| 1452040_a_at | Cdca3 | Cell division cycle associated 3 | 14793 | 6 | −1.648974967 | 5.94876901 | 2.49E-06 | 0.003033223 |
| 1419152_at | 2810417H13Rik | RIKEN cdna 2810417H13 gene | 68026 | 9 | −1.582759678 | 3.998568419 | 6.26E-05 | 0.027960233 |
| 1417019_a_at | Cdc6 | Cell division cycle 6 homolog (S. cerevisiae) | 23834 | 11 | −1.57591995 | 4.26547158 | 9.43E-06 | 0.009050868 |
| 1452954_at | Ube2c | Ubiquitin-conjugating enzyme E2C | 68612 | 2 | −1.565753358 | 5.76772749 | 0.000301765 | 0.077329052 |
| 1416309_at | Nusap1 | Nucleolar and spindle associated protein 1 | 108907 | 2 | −1.536420918 | 5.305367114 | 7.84E-06 | 0.007860968 |
| 1419513_a_at | Ect2 | Ect2 oncogene | 13605 | 3 | −1.480046133 | 5.802155734 | 2.41E-07 | 0.00041802 |
| 1417938_at | Rad51ap1 | RAD51 associated protein 1 | 19362 | 6 | −1.405538953 | 4.623888646 | 3.81E-06 | 0.004290985 |
| 1423775_s_at | Prc1 | Protein regulator of cytokinesis 1 | 233406 | 7 | −1.390411141 | 5.264829948 | 0.000213078 | 0.06673636 |
| 1415810_at | Uhrf1 | Ubiquitin-like, containing PHD and RING finger domains, 1 | 18140 | 17 | −1.338229755 | 5.971743604 | 0.000205735 | 0.066277423 |
| 1439260_a_at | Enpp3 | Ectonucleotide pyrophosphatase/phosphodiesterase 3 | 209558 | 10 | −1.323071458 | 5.161679137 | 0.000111763 | 0.042717156 |
| 1423774_a_at | Prc1 | Protein regulator of cytokinesis 1 | 233406 | 7 | −1.317941862 | 5.185417817 | 4.08E-05 | 0.022467357 |
| 1418264_at | Cenpk | Centromere protein K | 60411 | 13 | −1.263246556 | 5.540393037 | 7.84E-06 | 0.007860968 |
| 1422430_at | Fignl1 | Fidgetin-like 1 | 60530 | 11 | −1.255234814 | 6.344925562 | 0.000333539 | 0.083110081 |
| 1436723_at | Cenpi | Centromere protein I | 102920 | X | −1.189208966 | 3.82424006 | 1.06E-05 | 0.0092458 |
| 1429499_at | Fbxo5 | F-box protein 5 | 67141 | 10 | −1.1853163 | 6.447051807 | 3.92E-05 | 0.02232997 |
| 1422535_at | Ccne2 | Cyclin E2 | 12448 | 4 | −1.171113511 | 6.971543851 | 4.20E-07 | 0.000676388 |
| 1452881_at | Gins2 | GINS complex subunit 2 (Psf2 homolog) | 272551 | 8 | −1.16739969 | 3.938680054 | 0.000263239 | 0.072392332 |
| 1417822_at | D17H6S56E-5 | DNA segment, Chr 17, human D6S56E 5 | 110956 | 17 | −1.162085782 | 5.963118686 | 3.78E-05 | 0.021849726 |
| 1455990_at | Kif23 | Kinesin family member 23 | 71819 | 9 | −1.133418604 | 4.171841101 | 8.20E-05 | 0.03454806 |
| 1417777_at | Ptgr1 | Prostaglandin reductase 1 | 67103 | 4 | −1.105405878 | 6.943139899 | 5.15E-05 | 0.026090601 |
| 1424156_at | Rbl1 | Retinoblastoma-like 1 (p107) | 19650 | 2 | −1.10458618 | 6.155772903 | 3.72E-05 | 0.021809078 |
| 1459401_at | −1.088747387 | 3.045176972 | 2.10E-05 | 0.013958609 | ||||
| 1417541_at | Hells | Helicase, lymphoid specific | 15201 | 19 | −1.067654825 | 6.879010181 | 1.93E-05 | 0.013394345 |
| 1453152_at | Mamdc2 | MAM domain containing 2 | 71738 | 19 | −1.056757423 | 5.224573346 | 5.69E-05 | 0.027027604 |
| 1448441_at | Cks1b | CDC28 protein kinase 1b | 54124 | 3 | −1.036997965 | 6.318610164 | 0.00021997 | 0.067098594 |
| 1439695_a_at | Kif20b | Kinesin family member 20B | 240641 | 19 | −1.006991525 | 4.429442051 | 0.000273481 | 0.074302888 |
| 1436808_x_at | Mcm5 | Minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae) | 17218 | 8 | −1.005425316 | 8.380764994 | 0.000103015 | 0.040400609 |
| 1429658_a_at | Smc2 | Structural maintenance of chromosomes 2 | 14211 | 4 | −1.005286029 | 6.983293269 | 5.87E-06 | 0.006306238 |
| 1422460_at | Mad2l1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 56150 | 6 | −0.999626502 | 7.697761259 | 3.16E-07 | 0.000528013 |
| 1456111_at | Fam55d | Family with sequence similarity 55, member D | 244853 | 9 | −0.988116342 | 8.738952078 | 0.000203043 | 0.065880755 |
| 1435089_at | 2010111I01Rik | RIKEN cdna 2010111I01 gene | 72061 | 13 | −0.958243159 | 4.790548699 | 7.11E-07 | 0.001002225 |
| 1452583_s_at | Galm | Galactose mutarotase | 319625 | 17 | −0.949792205 | 4.160765615 | 0.000248664 | 0.069658474 |
| AFFX-ThrX-M_at | −0.942616139 | 7.729716391 | 0.000122543 | 0.046443984 | ||||
| 1450842_a_at | Cenpa | Centromere protein A | 12615 | 5 | −0.938800118 | 5.988464134 | 0.000222082 | 0.067098594 |
| 1415945_at | Mcm5 | Minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae) | 17218 | 8 | −0.936860277 | 4.054367544 | 0.000259144 | 0.07170327 |
| 1448891_at | Fcrls | Fc receptor-like S, scavenger receptor | 80891 | 3 | −0.925376894 | 9.318029399 | 0.000183309 | 0.06124021 |
| 1416757_at | Zwilch | Zwilch, kinetochore associated, homolog (Drosophila) | 68014 | 9 | −0.902194387 | 6.309892384 | 0.000168534 | 0.058469554 |
| 1418334_at | Dbf4 | DBF4 homolog (S. cerevisiae) | 27214 | 5 | −0.893927151 | 6.841390964 | 0.000191143 | 0.062925136 |
| 1436174_at | Atad2 | Atpase family, AAA domain containing 2 | 70472 | 15 | −0.882577585 | 7.600552606 | 1.86E-05 | 0.013106888 |
| AFFX-r2-Bs-dap-5_at | −0.86945837 | 10.53042728 | 1.82E-05 | 0.013106888 | ||||
| AFFX-DapX-5_at | −0.860133556 | 10.05521236 | 2.10E-05 | 0.013958609 | ||||
| 1416251_at | Mcm6 | Minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 17219 | 1 | −0.858315987 | 8.325615765 | 0.000233438 | 0.06748906 |
| 1429660_s_at | Smc2 | Structural maintenance of chromosomes 2 | 14211 | 4 | −0.856002583 | 7.216526604 | 1.24E-05 | 0.009654221 |
| 1417458_s_at | Cks2 | CDC28 protein kinase regulatory subunit 2 | 66197 | 13 | −0.839316362 | 7.86782249 | 1.11E-05 | 0.0092458 |
| 1416868_at | Cdkn2c | Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 12580 | 4 | −0.836129956 | 6.12344177 | 0.000223428 | 0.067098594 |
| 1417457_at | Cks2 | CDC28 protein kinase regulatory subunit 2 | 66197 | 13 | −0.81379049 | 7.723402569 | 2.50E-05 | 0.015890112 |
| 1438852_x_at | Mcm6 | Minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 17219 | 1 | −0.749758108 | 7.64596611 | 0.000402883 | 0.092676501 |
| 1443278_at | −0.744465639 | 3.795201185 | 5.01E-05 | 0.025691504 | ||||
| 1416698_a_at | Cks1b | CDC28 protein kinase 1b | 54124 | 3 | −0.722795196 | 9.78476954 | 3.68E-05 | 0.021809078 |
| 1439269_x_at | Mcm7 | Minichromosome maintenance deficient 7 (S. cerevisiae) | 17220 | 5 | −0.722636555 | 7.202355749 | 4.05E-05 | 0.022467357 |
| 1439040_at | Cenpe | Centromere protein E | 229841 | 3 | −0.719923535 | 4.673443364 | 0.000243326 | 0.069457388 |
| 1430447_a_at | Lair1 | Leukocyte-associated Ig-like receptor 1 | 52855 | 7 | −0.714377106 | 6.333351745 | 0.000317802 | 0.079628911 |
| 1424321_at | Rfc4 | Replication factor C (activator 1) 4 | 106344 | 16 | −0.712575965 | 6.803183771 | 1.03E-05 | 0.0092458 |
| 1429364_at | 4930579G24Rik | RIKEN cdna 4930579G24 gene | 75939 | 3 | −0.693804864 | 5.801650455 | 0.000444319 | 0.099204172 |
| 1417305_at | Speg | SPEG complex locus | 11790 | 1 | −0.69237419 | 5.560929585 | 4.88E-05 | 0.025316027 |
| 1424265_at | Npl | N-acetylneuraminate pyruvate lyase | 74091 | 1 | −0.686117769 | 8.236312861 | 6.73E-05 | 0.029399408 |
| 1455033_at | Fam102b | Family with sequence similarity 102, member B | 329739 | 3 | −0.682945448 | 9.023990641 | 5.82E-05 | 0.027040374 |
| 1439436_x_at | −0.682001634 | 8.458610109 | 2.89E-05 | 0.017856664 | ||||
| AFFX-DapX-M_at | −0.669552741 | 12.00937024 | 7.34E-05 | 0.031511664 | ||||
| 1419838_s_at | Plk4 | Polo-like kinase 4 (Drosophila) | 20873 | 3 | −0.661731363 | 7.369464895 | 6.19E-05 | 0.027939309 |
| AFFX-r2-Bs-dap-M_at | −0.656068752 | 12.16297427 | 6.78E-05 | 0.029399408 | ||||
| 1423809_at | Tcf19 | Transcription factor 19 | 106795 | 17 | −0.655651 | 6.697811615 | 0.000357756 | 0.086748212 |
| 1418403_at | −0.646745558 | 3.99343285 | 9.90E-06 | 0.0092458 | ||||
| 1459371_at | −0.639703594 | 3.330641988 | 0.000111201 | 0.042717156 | ||||
| 1427275_at | Smc4 | Structural maintenance of chromosomes 4 | 70099 | 3 | −0.636699981 | 9.889336813 | 0.000226357 | 0.067098594 |
| 1427276_at | Smc4 | Structural maintenance of chromosomes 4 | 70099 | 3 | −0.636392607 | 8.167608285 | 1.17E-05 | 0.0092458 |
| 1419585_at | Rp2h | Retinitis pigmentosa 2 homolog (human) | 19889 | X | −0.625314312 | 6.995631785 | 0.000247986 | 0.069658474 |
| 1448635_at | Smc2 | Structural maintenance of chromosomes 2 | 14211 | 4 | −0.615253418 | 9.046606184 | 0.00026535 | 0.072530616 |
| 1440471_x_at | −0.610865075 | 5.566366706 | 0.000210867 | 0.06673636 | ||||
| 1438320_s_at | Mcm7 | Minichromosome maintenance deficient 7 (S. cerevisiae) | 17220 | 5 | −0.593464087 | 9.166719577 | 0.000134177 | 0.049602424 |
| 1455439_a_at | Lgals1 | Lectin, galactose binding, soluble 1 | 16852 | 15 | −0.587410622 | 12.94937502 | 0.000138487 | 0.050779673 |
| 1415878_at | Rrm1 | Ribonucleotide reductase M1 | 20133 | 7 | −0.584321844 | 8.036876453 | 3.23E-06 | 0.003834443 |
| 1417419_at | Ccnd1 | Cyclin D1 | 12443 | 7 | −0.576144077 | 9.201498108 | 0.000387426 | 0.09148321 |
| 1416118_at | Trim59 | Tripartite motif-containing 59 | 66949 | 3 | −0.556665238 | 10.25174171 | 3.04E-05 | 0.01850647 |
| 1417506_at | Gmnn | Geminin | 57441 | 13 | −0.542861413 | 8.155624224 | 9.34E-05 | 0.038311018 |
| 1439076_at | Dhx29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 | 218629 | 13 | −0.541516701 | 3.938488955 | 0.000366949 | 0.088501495 |
| 1449251_at | Ndp | Norrie disease (pseudoglioma) (human) | 17986 | X | −0.541343277 | 5.218867522 | 0.000298301 | 0.077329052 |
| 1442178_at | −0.533345869 | 2.585014581 | 0.000431192 | 0.097236031 | ||||
| 1417420_at | Ccnd1 | Cyclin D1 | 12443 | 7 | −0.52516431 | 10.73705667 | 0.000340985 | 0.084036867 |
| 1416544_at | Ezh2 | Enhancer of zeste homolog 2 (Drosophila) | 14056 | 6 | −0.50771044 | 7.078829441 | 0.000223554 | 0.067098594 |
| 1434400_at | Tgif2 | TGFB-induced factor homeobox 2 | 228839 | 2 | −0.500269195 | 4.697314191 | 0.00014771 | 0.052872074 |
| 1434828_at | Fam102b | Family with sequence similarity 102, member B | 329739 | 3 | −0.497665308 | 10.1660915 | 6.78E-07 | 0.00098628 |
| 1449839_at | Casp3 | Caspase 3 | 12367 | 8 | −0.469257971 | 7.646475442 | 2.31E-05 | 0.014852111 |
| 1450105_at | Adam10 | A disintegrin and metallopeptidase domain 10 | 11487 | 9 | −0.452151362 | 7.730866025 | 0.000224757 | 0.067098594 |
| 1445449_at | −0.445871009 | 3.041247901 | 0.000355695 | 0.086714534 | ||||
| 1451577_at | Zbtb20 | Zinc finger and BTB domain containing 20 | 56490 | 16 | −0.440401975 | 8.795279588 | 0.000111605 | 0.042717156 |
| 1434547_at | Cpd | Carboxypeptidase D | 12874 | 11 | −0.440224965 | 9.1896364 | 5.69E-05 | 0.027027604 |
| 1452241_at | Topbp1 | Topoisomerase (DNA) II binding protein 1 | 235559 | 9 | −0.439137196 | 8.888184976 | 4.17E-05 | 0.02265456 |
| 1458847_at | −0.40488218 | 5.413331848 | 0.000385844 | 0.09148321 | ||||
| 1426478_at | Rasa1 | RAS p21 protein activator 1 | 218397 | 13 | −0.403270797 | 7.383508116 | 0.00038507 | 0.09148321 |
| 1458440_at | Cytsb | Cytospin B | 432572 | 11 | −0.402496123 | 8.709958419 | 0.000235806 | 0.067739411 |
| 1429735_at | Qk | Quaking | 19317 | 17 | −0.399851567 | 9.905073814 | 6.87E-08 | 0.000147519 |
| 1441466_at | Tra2b | Transformer 2 beta homolog (Drosophila) | 20462 | 16 | −0.39869007 | 7.189886877 | 0.000315419 | 0.079473168 |
| 1419270_a_at | Dut | Deoxyuridine triphosphatase | 110074 | 2 | −0.389310333 | 8.195464338 | 0.000284278 | 0.076773716 |
| 1433670_at | Emp2 | Epithelial membrane protein 2 | 13731 | 16 | −0.388645004 | 8.865683907 | 8.66E-05 | 0.036146904 |
| 1421955_a_at | Nedd4 | Neural precursor cell expressed, developmentally down-regulated 4 | 17999 | 9 | −0.373977817 | 11.23710511 | 8.87E-07 | 0.00117645 |
| 1449408_at | Jam2 | Junction adhesion molecule 2 | 67374 | 16 | −0.371454368 | 7.976322911 | 0.000197267 | 0.064470562 |
| 1424459_at | Lpcat1 | Lysophosphatidylcholine acyltransferase 1 | 210992 | 13 | −0.370424051 | 7.748290994 | 6.58E-05 | 0.029084529 |
| 1416012_at | Ehd1 | EH-domain containing 1 | 13660 | 19 | −0.365152057 | 2.352790173 | 6.07E-05 | 0.027662448 |
| 1426300_at | Alcam | Activated leukocyte cell adhesion molecule | 11658 | 16 | −0.353828749 | 9.633088206 | 0.000372299 | 0.089314111 |
| 1420475_at | Mtpn | Myotrophin | 14489 | 6 | −0.346958608 | 10.89488202 | 1.85E-05 | 0.013106888 |
| 1448942_at | Gng11 | Guanine nucleotide binding protein (G protein), gamma 11 | 66066 | 6 | −0.340659661 | 11.45532439 | 0.000189529 | 0.062852558 |
| 1421871_at | Sh3bgrl | SH3-binding domain glutamic acid-rich protein like | 56726 | X | −0.339792915 | 9.714114518 | 0.000154802 | 0.054544833 |
| 1416452_at | Oat | Ornithine aminotransferase | 18242 | 7 | −0.334565945 | 10.61591638 | 0.00022056 | 0.067098594 |
| 1457638_x_at | Rfc2 | Replication factor C (activator 1) 2 | 19718 | 5 | −0.332467053 | 3.787763354 | 3.29E-05 | 0.019765971 |
| 1455009_at | Cpd | Carboxypeptidase D | 12874 | 11 | −0.332417447 | 11.02153966 | 4.69E-05 | 0.024861027 |
| 1425148_a_at | −0.330492679 | 9.911770375 | 6.50E-06 | 0.006822235 | ||||
| 1456864_at | −0.329690668 | 7.637260202 | 0.000212898 | 0.06673636 | ||||
| 1452364_at | Suz12 | Suppressor of zeste 12 homolog (Drosophila) | 52615 | 11 | −0.318459702 | 8.755295551 | 1.66E-05 | 0.012294056 |
| 1428229_at | Prkd3 | Protein kinase D3 | 75292 | 17 | −0.315849633 | 9.210570296 | .000175439 | 0.059828297 |
| 1436584_at | Spry2 | Sprouty homolog 2 (Drosophila) | 24064 | 14 | −0.315505191 | 9.405170016 | 0.000441727 | 0.099116095 |
| 1431645_a_at | Gdi2 | Guanosine diphosphate (GDP) dissociation inhibitor 2 | 14569 | 13 | −0.311816557 | 9.222129783 | 0.000158772 | 0.055510036 |
| 1431777_a_at | Hmgn3 | High mobility group nucleosomal binding domain 3 | 94353 | 9 | −0.28490797 | 9.531069895 | 0.000290756 | 0.077073517 |
| 1421867_at | Nr3c1 | Nuclear receptor subfamily 3, group C, member 1 | 14815 | 18 | −0.273389702 | 9.507809306 | 5.67E-06 | 0.006241408 |
| 1421163_a_at | Nfia | Nuclear factor I/A | 18027 | 4 | −0.270353912 | 9.311783627 | 0.000227624 | 0.067098594 |
| 1427418_a_at | Hif1a | Hypoxia inducible factor 1, alpha subunit | 15251 | 12 | −0.269264102 | 12.12968325 | 9.73E-05 | 0.039170935 |
| 1456630_x_at | Son | Son DNA binding protein | 20658 | 16 | −0.259912656 | 5.514125234 | 0.000102045 | 0.040371446 |
| 1455665_at | −0.250923844 | 9.000863357 | 0.000288103 | 0.076961632 | ||||
| 1434875_a_at | Hmgn3 | High mobility group nucleosomal binding domain 3 | 94353 | 9 | −0.216455623 | 11.23865582 | 0.000395541 | 0.092468287 |
| 1417622_at | Slc12a2 | Solute carrier family 12, member 2 | 20496 | 18 | −0.209517839 | 12.84701076 | 0.000288386 | 0.076961632 |
| 1421594_a_at | Sytl2 | Synaptotagmin-like 2 | 83671 | 7 | −0.196868664 | 10.34467457 | 0.000146948 | 0.052872074 |
| 1426477_at | Rasa1 | RAS p21 protein activator 1 | 218397 | 13 | −0.183365681 | 9.77002577 | 0.000397748 | 0.092468287 |
| 1418664_at | Mpdz | Multiple PDZ domain protein | 17475 | 4 | −0.173832728 | 9.811997929 | 0.000340617 | 0.084036867 |
| 1437735_at | Ppp1r12a | Protein phosphatase 1, regulatory (inhibitor) subunit 12A | 17931 | 10 | −0.17099414 | 10.86996247 | 8.74E-05 | 0.036146904 |
| 1417124_at | Dstn | Destrin | 56431 | 2 | −0.165792871 | 12.23140999 | 5.72E-07 | 0.000859868 |
| 1444731_at | Pde4b | Phosphodiesterase 4B, camp specific | 18578 | 4 | −0.161464191 | 2.194657586 | 4.32E-05 | 0.023203628 |
| 1419258_at | Tcea1 | Transcription elongation factor A (SII) 1 | 21399 | 1 | −0.155724152 | 9.279614137 | 0.000403207 | 0.092676501 |
| 1458650_at | 0.111574996 | 2.185422735 | 1.29E-05 | 0.009837963 | ||||
| 1431710_at | Cmtm1 | CKLF-like MARVEL transmembrane domain containing 1 | 353509 | 8 | 0.129419017 | 2.192752448 | 0.000128189 | 0.047780613 |
| 1458999_at | Mrps10 | Mitochondrial ribosomal protein S10 | 64657 | 17 | 0.144462567 | 2.196160229 | 1.08E-05 | 0.0092458 |
| 1447397_at | Fam154b | Family with sequence similarity 154, member B | 330577 | 7 | 0.1765539 | 2.351407136 | 0.000183165 | 0.06124021 |
| 1416341_at | Polr2c | Polymerase (RNA) II (DNA directed) polypeptide C | 20021 | 8 | 0.17770492 | 10.14198093 | 8.09E-05 | 0.034417928 |
| 1418854_at | Birc2 | Baculoviral IAP repeat-containing 2 | 11797 | 9 | 0.181107841 | 9.091052204 | 0.000404809 | 0.092676501 |
| 1421197_a_at | Acin1 | Apoptotic chromatin condensation inducer 1 | 56215 | 14 | 0.203070117 | 8.011609635 | 0.000407345 | 0.092786302 |
| 1456456_x_at | Mela | Melanoma antigen | 17276 | 8 | 0.208254298 | 2.202691498 | 1.13E-05 | 0.0092458 |
| 1415744_at | H2-Ke2 | H2-K region expressed gene 2 | 14976 | 17 | 0.229447346 | 9.962634591 | 5.72E-05 | 0.027027604 |
| 1415825_s_at | 0.250431438 | 9.242002243 | 1.99E-06 | 0.002499325 | ||||
| 1445796_at | 0.253687541 | 2.287014411 | 1.96E-06 | 0.002499325 | ||||
| 1430355_a_at | Steap3 | STEAP family member 3 | 68428 | 1 | 0.259642804 | 2.231116337 | 3.96E-05 | 0.02232997 |
| 1434128_a_at | Zfp574 | Zinc finger protein 574 | 232976 | 7 | 0.272715738 | 8.382992378 | 9.57E-05 | 0.038893825 |
| 1424105_a_at | Pttg1 | Pituitary tumor-transforming gene 1 | 30939 | 11 | 0.310834954 | 9.260582038 | 0.000298703 | 0.077329052 |
| 1421266_s_at | Nfkbib | Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta | 18036 | 7 | 0.330314423 | 6.829432477 | 5.35E-05 | 0.026535058 |
| 1452323_at | Spryd3 | SPRY domain containing 3 | 223918 | 15 | 0.343767284 | 6.359462159 | 0.000314459 | 0.079473168 |
| 1449946_a_at | Zfp593 | Zinc finger protein 593 | 68040 | 4 | 0.366799342 | 2.235778523 | 1.58E-07 | 0.000296868 |
| 1428955_x_at | Slc9a3r2 | Solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 | 65962 | 17 | 0.380216255 | 5.670220407 | 0.000345934 | 0.084793329 |
| 1445521_at | Elavl1 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) | 15568 | 8 | 0.424761143 | 2.580184206 | 9.97E-05 | 0.039782909 |
| 1447521_x_at | Arhgap39 | Rho gtpase activating protein 39 | 223666 | 15 | 0.455727425 | 7.791080283 | 3.55E-06 | 0.004110779 |
| 1444687_at | C1ql2 | Complement component 1, q subcomponent-like 2 | 226359 | 1 | 0.455890584 | 2.232967485 | 5.21E-05 | 0.026090601 |
| 1425099_a_at | Arntl | Aryl hydrocarbon receptor nuclear translocator-like | 11865 | 7 | 0.471624543 | 6.926906582 | 0.000232857 | 0.06748906 |
| 1455625_at | Taf10 | TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor | 24075 | 7 | 0.472883669 | 6.386041289 | 0.000414451 | 0.093930531 |
| 1436080_at | AW011738 | Expressed sequence AW011738 | 100382 | 4 | 0.577699956 | 3.208346666 | 0.000146694 | 0.052872074 |
| 1437895_at | Ano8 | Anoctamin 8 | 382014 | 8 | 0.578429707 | 2.982308738 | 2.68E-05 | 0.016775714 |
| 1429683_at | Ttpal | Tocopherol (alpha) transfer protein-like | 76080 | 2 | 0.634696898 | 2.297481209 | 7.85E-07 | 0.001072929 |
| 1456341_a_at | Klf9 | Kruppel-like factor 9 | 16601 | 19 | 0.647866078 | 13.56198497 | 0.000221584 | 0.067098594 |
| 1459211_at | Gli2 | GLI-Kruppel family member GLI2 | 14633 | 1 | 0.656120515 | 6.28713459 | 0.000296285 | 0.077329052 |
| 1456551_at | 0.663002676 | 6.58802102 | 1.17E-05 | 0.0092458 | ||||
| 1451707_s_at | Slc41a3 | Solute carrier family 41, member 3 | 71699 | 6 | 0.708570154 | 4.221361487 | 0.000397174 | 0.092468287 |
| 1434202_a_at | Fam107a | Family with sequence similarity 107, member A | 268709 | 14 | 0.70935785 | 12.42842253 | 0.000126093 | 0.047391057 |
| 1416822_at | Dgcr14 | Digeorge syndrome critical region gene 14 | 27886 | 16 | 0.711503522 | 3.810428731 | 2.15E-05 | 0.014070373 |
| 1460459_at | Paqr5 | Progestin and adipoq receptor family member V | 74090 | 9 | 0.71385502 | 2.508969498 | 5.75E-05 | 0.027027604 |
| 1427091_at | Znfx1 | Zinc finger, NFX1-type containing 1 | 98999 | 2 | 0.758493811 | 5.854061725 | 0.000247099 | 0.069658474 |
| 1438355_at | Tmem90a | Transmembrane protein 90a | 627191 | 12 | 0.774431363 | 2.613623643 | 1.07E-05 | 0.0092458 |
| 1434203_at | Fam107a | Family with sequence similarity 107, member A | 268709 | 14 | 0.815384732 | 10.5462952 | 0.00017643 | 0.059828297 |
| 1418710_at | Cd59a | CD59a antigen | 12509 | 2 | 0.859536149 | 9.678137754 | 1.25E-08 | 3.76E-05 |
| 1439825_at | Dtx3l | Deltex 3-like (Drosophila) | 209200 | 16 | 0.894876503 | 6.398634387 | 0.000314298 | 0.079473168 |
| 1421911_at | Stat2 | Signal transducer and activator of transcription 2 | 20847 | 10 | 0.904194187 | 3.706003989 | 5.88E-05 | b0.027076306 |
| 1436763_a_at | Klf9 | Kruppel-like factor 9 | 16601 | 19 | 0.940687065 | 8.705507464 | 0.000292223 | 0.077073517 |
| 1421037_at | Npas2 | Neuronal PAS domain protein 2 | 18143 | 1 | 0.942006114 | 5.466528073 | 9.37E-06 | 0.009050868 |
| 1429830_a_at | Cd59a | CD59a antigen | 12509 | 2 | 0.946400942 | 8.930716143 | 4.64E-08 | 0.000110118 |
| 1426915_at | Dapk1 | Death associated protein kinase 1 | 69635 | 13 | 0.946743286 | 6.888382903 | 2.04E-07 | 0.00036876 |
| 1450484_a_at | Cmpk2 | Cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial | 22169 | 12 | 0.963172651 | 8.200096609 | 1.48E-05 | 0.011095655 |
| 1428306_at | Ddit4 | DNA-damage-inducible transcript 4 | 74747 | 10 | 0.976582722 | 9.883199197 | 5.50E-05 | 0.0269511 |
| 1435918_at | Fam107a | Family with sequence similarity 107, member A | 268709 | 14 | 1.066937661 | 5.301492621 | 0.000207205 | 0.066277746 |
| 1417141_at | Igtp | Interferon gamma induced gtpase | 16145 | 11 | 1.140412802 | 7.957198967 | 0.000300716 | 0.077329052 |
| 1419714_at | Cd274 | CD274 antigen | 60533 | 19 | 1.198293107 | 4.692778191 | 0.000153394 | 0.054474272 |
| 1460603_at | Samd9l | Sterile alpha motif domain containing 9-like | 209086 | 6 | 1.300826076 | 7.286107011 | 0.000232948 | 0.06748906 |
| 1419083_at | Tnfsf11 | Tumor necrosis factor (ligand) superfamily, member 11 | 21943 | 14 | 1.333472182 | 2.497808653 | 0.000251966 | 0.070147731 |
| 1419699_at | Scgb3a1 | Secretoglobin, family 3A, member 1 | 68662 | 11 | 1.437983381 | 3.135180092 | 4.74E-05 | 0.024861027 |
| 1458089_at | 1.51422121 | 2.804055563 | 1.14E-05 | 0.0092458 | ||||
| 1431213_a_at | LOC67527 | Murine leukemia retrovirus | 67527 | 18 | 2.086600168 | 7.016864344 | 2.06E-05 | 0.013958609 |
| 1455869_at | 2.531706562 | 7.572095274 | 0.000170292 | 0.058628642 |
In this table, we include the 202 differentially expressed Affymetrix probe sets. Chr, chromosomal number; logFC, log2 fold change value for that probe set in trkB.T1 KO spinal cord compared with WT; AveExpr, average signal intensity for each probe set across the 1 d dataset.