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. 2011 Aug;22(4):175–178. doi: 10.5830/CVJA-2010-058

Table 1. Proteins Identified In Obese Female Mice: Mitochondrial Energy Metabolism.

Spot SSP Mr (Da) pI Mascot score Protein name Swiss prot accession number % Sequence coverage No of peptides Fold increase or decrease Functional group or function
1 2305 56265 5.19 873 ATP synthase subunit beta, P56480 44 18 2.7 ATP synthesis, (catalytic subunit)
2* 5002 18664 5.52 273 ATP synthase D chain Q9DCX2 70 11 2.5 ATP synthesis, (rotational mechanism)
3* 6003 53420 5.75 280 Ubiquinol cytochrome-C reductase core protein 1 Q9CZ13 21 7 –2.1 Electron transport
4 8406 59830 9.22 693 ATP synthase subunit alpha P56757 30 15 14.9 ATP synthesis (regulatory subunit)
5 3101 27640 5.19 297 NADH dehydrogenase flavoprotein 2 Q9D6J6 45 9 –1.8 Electron transfer
6 2903 80724 5.51 563 NADH ubiquinone oxidoreductase 75 kDa subunit Q91VD9 26 18 –2 Electron transfer
7* 9302 35360 8.62 623 Electron transfer flavoprotein subunit alpha Q99LC5 51 15 5.9 Electron transfer

Data represent differentially expressed proteins between control and obese female mice. Only proteins that were significantly different are reported (p < 0.05). The SSP number is assigned by the PDQuest software program (Bio-Rad, Hercules CA). *Proteins identified in two or more independent experiments.

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