Table I.
Pill count data and estimation of adherence
| All study visits | Number of visits | % of visits included |
|---|---|---|
| Scheduled visits | 61,279 | |
| Protocol specified treatment interruption | 2,164 | |
| Visits assessed for pill count completeness | 59,115 | 100.0% |
| Calculable pill count adherence | 52,635 | 89.0% |
| Incalculable adherence | 6,480 | 11.0% |
| Missing pill count dataa | 3,487 | 5.9% |
| Multiple bottles in circulation | 2,993 | 5.1% |
| Pills returned at non adjacent visitsb | 904 | 1.5% |
| Multiple bottles returned at a visit | 1,924 | 3.3% |
| Multiple bottles dispensedc | 165 | 0.3% |
a
Bottles forgotten or lost
b
The participant has more than one pill bottle as a result of not returning a bottle at a previous visit or having multiple bottles dispensed at a visit.
c
Multiple bottles were dispensed in situations where the participant would be unable to come to the clinic and would otherwise be without study drug.