Table 4.
HWE values of SCD1 and their genotype frequencies
|
SNP |
Caucasians |
Asians |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Males |
Females |
Males |
Females |
|||||||||
| HWE | Major allele | MAF | HWE | Major allele | MAF | HWE | Major allele | MAF | HWE | Major allele | MAF | |
| rs10883463 |
0.79 |
T |
0.09 |
0.99 |
T |
0.10 |
0.99 |
T |
0.01 |
0.98 |
T |
1.9•10-3 |
| rs417669878 |
0.79 |
G |
0.42 |
0.99 |
G |
0.42 |
0.98 |
G |
0.26 |
0.98 |
G |
0.28 |
| rs2060792 |
0.83 |
A |
0.26 |
0.99 |
A |
0.29 |
0.99 |
A |
0.39 |
0.98 |
A |
0.31 |
| rs3071 |
0.79 |
T |
0.29 |
0.99 |
T |
0.31 |
0.98 |
T |
0.27 |
0.98 |
T |
0.28 |
| rs3793766 |
0.79 |
C |
0.12 |
0.99 |
C |
0.08 |
0.99 |
C |
0.17 |
0.98 |
C |
0.18 |
| rs3793767 |
0.82 |
T |
0.40 |
0.99 |
T |
0.37 |
0.98 |
T |
0.45 |
0.98 |
T |
0.35 |
| rs490726 |
0.67 |
T |
0.22 |
0.99 |
T |
0.19 |
0.99 |
T |
0.23 |
0.98 |
T |
0.28 |
| rs522951 |
0.83 |
G |
0.48 |
0.99 |
G |
0.49 |
0.99 |
G |
0.42 |
0.98 |
G |
0.32 |
| rs569184 |
0.79 |
C |
0.12 |
0.99 |
C |
0.08 |
0.99 |
C |
0.20 |
0.98 |
C |
0.28 |
| rs575338 | 0.79 | G | 0.15 | 0.99 | G | 0.13 | NP | G | 0.98 | G | 5.6•10-3 | |
SNPs with HWE p-values less than 0.05 are not in Hardy-Weinberg Equilibrium. Caucasian Males: n = 113; Caucasian females: n = 298; Asian Males: n = 98; Asian Females: n = 277. Abbreviations: HWE, Hardy-Weinberg Equilibrium p-values; MAF, minor allele frequency; NP, not polymorphic (MAF = 0).