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. 2013 Jul 18;10:50. doi: 10.1186/1743-7075-10-50

Table 5.

Estimates of D9D activity according to genotype for each SCD1 SNP in Caucasians

 
[18:2c9t11/18:1 t11] in males
[18:2c9t11/18:1 t11] in females
  MM Mm mm P-value MM Mm mm P-value
rs10883463
1.077 ± 0.036a
0.769 ± 0.048b
-
<0.01*
1.206 ± 0.036
1.244 ± 0.061
1.505 ± 0.170
0.75
rs17669878
1.079 ± 0.070
0.977 ± 0.040
1.064 ± 0.076
0.23
1.248 ± 0.041
1.195 ± 0.050
1.207 ± 0.074
0.72
rs2060792
1.015 ± 0.037
0.998 ± 0.061
1.215 ± 0.179
0.62
1.251 ± 0.053
1.175 ± 0.036
1.229 ± 0.088
0.58
rs3071
1.037 ± 0.052
1.024 ± 0.046
0.913 ± 0.051
0.78
1.202 ± 0.031
1.224 ± 0.059
1.238 ± 0.105
0.87
rs3793766
1.003 ± 0.036
1.083 ± 0.078
1.200
0.59
1.217 ± 0.035
1.209 ± 0.057
1.084 ± 0.391
0.94
rs3793767
0.939 ± 0.042
1.043 ± 0.051
1.111 ± 0.097
0.25
1.178 ± 0.043
1.252 ± 0.052
1.200 ± 0.054
0.81
rs490726
1.073 ± 0.042
0.960 ± 0.053
0.856 ± 0.344
0.23
1.215 ± 0.041
1.217 ± 0.046
1.229 ± 0.107
0.99
rs522951
1.044 ± 0.046
1.011 ± 0.050
1.019 ± 0.081
0.78
1.125 ± 0.055
1.252 ± 0.049
1.237 ± 0.048
0.42
rs569184
1.010 ± 0.036
1.060 ± 0.079
1.200
0.72
1.223 ± 0.035
1.198 ± 0.054
0.637 ± 0.055
0.38
rs575338 1.024 ± 0.042 1.024 ± 0.045 1.003 ± 0.155 0.99 1.193 ± 0.029 1.291 ± 0.098 1.188 ± 0.084 0.44

Results of analysis of 10 SNPs from SCD1 for associations with D9D activity index [182c9t11:181 t11]. Different letters (a or b) denote values that are significantly different between groups. P-values were determined using linear regression models which were adjusted for BMI, age, % of Total Energy from Dietary Fat and physical activity. Caucasian Males: n = 113; Caucasian females: n = 298; Asian Males: n = 98; Asian Females: n = 277. Abbreviations: D9D, delat-9-desaturase; M, major; m, minor; ‘-’ indicates that no subjects with this genotype were present in this population.