Table 6.

Estimates of D9D activity according to genotype for each SCD1 SNP in Asians

	[18:2c9t11/18:1 t11] in males				[18:2c9t11/18:1 t11] in females
	MM	Mm	mm	P-value	MM	Mm	mm	P-value
rs10883463	1.039 ± 0.041	0.813 ± 0.064	-	0.46	1.085 ± 0.027	0.783	-	0.23
rs17669878	1.094 ± 0.059	0.966 ± 0.052	0.910 ± 0.118	0.18	1.035 ± 0.035	1.139 ± 0.043	1.061 ± 0.096	0.28
rs2060792	0.949 ± 0.049	1.052 ± 0.064	1.185 ± 0.107	0.27	1.090 ± 0.040	1.058 ± 0.038	1.185 ± 0.084	0.37
rs3071	1.069 ± 0.061	0.959 ± 0.048	1.103 ± 0.121	0.34	1.052 ± 0.038	1.143 ± 0.041	0.939 ± 0.063	0.11
rs3793766	1.035 ± 0.047	1.053 ± 0.081	0.752 ± 0.036	0.88	1.072 ± 0.030	1.117 ± 0.056	0.906 ± 0.081	0.59
rs3793767	0.993 ± 0.057	1.028 ± 0.058	1.120 ± 0.104	0.66	1.109 ± 0.044	1.051 ± 0.037	1.120 ± 0.067	0.54
rs490726	1.035 ± 0.048	1.070 ± 0.077	0.795 ± 0.051	0.68	1.056 ± 0.034	1.128 ± 0.044	1.038 ± 0.101	0.19
rs522951	0.975 ± 0.053	1.030 ± 0.062	1.164 ± 0.102	0.40	1.095 ± 0.041	1.058 ± 0.038	1.156 ± 0.080	0.42
rs569184	1.041 ± 0.049	1.052 ± 0.076	0.807 ± 0.064	0.86	1.045 ± 0.034	1.129 ± 0.046	1.070 ± 0.093	0.25
rs575338	N/A				1.082 ± 0.027	0.815 ± 0.143	-	0.47

Results of analysis of 10 SNPs from SCD1 for associations with D9D activity index [182c9t11:181 t11]. P-values were determined using linear regression models which were adjusted for BMI, age, % of Total Energy from Dietary Fat and physical activity. Caucasian Males: n = 113; Caucasian females: n = 298; Asian Males: n = 98; Asian Females: n = 277. Abbreviations: D9D, delat-9-desaturase; M, major; m, minor; na, not applicable; ‘-’ indicates that no subjects with this genotype were present in this population.