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Functional transfer constant map of HCC during sunitinib therapy. Coronal enhanced MR T1-weighted images (A, B) and functional transfer constant (Ktrans) maps from MR perfusion (C, D) at baseline and after 2-week of sunitinib therapy in a 47-year-old man with HCC (arrows). After two weeks of treatment with sunitinib, HCC showed a 96% drop of Ktrans, which presented a conspicuity of permeability change.
