Table 1. Template modeling scores [TM] and root mean square deviation scores (RMSD) for the comparison of structural similarities between scFvs.

	TscFv		BscFv
	S9/P2	BDC2.5	D9	D9mut
D9	[0.94133]; (1.22)	[0.83072]; (2.67)	[1]; (0)	[0.60388]; (1.96)
S9/P2	[1]; (0)	[0.85166]; (2.77)	–	–

The higher the template modeling score [TM] and the lower the root mean square deviation score (RMSD) the more closely two structures are related. Comparison of two identical structures (D9 and S9/P2 each with itself) yields 1 for the TM score and 0 for the RMSD score. The TM score weighting algorithm is less sensitive to distant than to close matches and is therefore a more sensitive measure for structural similarity than the RMSD score [46].