Table 3.
DNA and CD4 evolution in 86 patients followed from the T1 to the T2 time point and detection of residual viraemia at T2
| Patients (n)** | Stable X4 (22) | Stable R5 (51) | Switch to X4 (6) | Switch to R5 (7) |
|---|---|---|---|---|
| CD4 T1a cells/mm3 |
431 (130 – 950) |
560 (54 – 1170) |
600 (330 – 860) |
420 (315 – 890) |
| CD4 T2a cells/mm3 |
520 (170 – 1110) |
615 (92 – 1291) |
540 (290 – 970) |
535 (420 – 740) |
| HIV DNA T1a Copies/106PBMCs |
41 (<5 – 657) |
95 (<5 – 892) |
75.5 (<5 – 532) |
196 (18 – 424) |
| HIV DNA T2a Copies/106PBMCs |
50.5 (<5 – 448) |
83 (<5 – 469) |
31 (<5 – 412) |
70 (7 – 147) |
| HIV RNA <2,5 copies/ml (n/total n patients and percentage)b | 2/22 (9.1%) | 19/51 (37.2%) | 4/6 (66.7%) | 1/7 (14.3%) |
aExpressed as median and range.
b Pearson chi2 (3)=11.5664, P = 0.0009).
** The stability of the tropism (stable X4 plus stable R5 vs switch to R5 plus switch to X4) was significant p< 0.0001.