Figure 9. Expression of GLTP in GlcCerS knockdown cells with impaired intracellular membrane trafficking caused by BFA and monensin.

A) ³H-sphinganine incorporation into GlcCer, GalCer and Cer as well as GLTP mRNA levels (filled circles) in GlcCerS KD HSF cells treated with BFA (0.01 µg/ml) and B) treated with monensin (5 µg/ml). Two asterisks (**), p<0.01 and three asterisks (***), p<0.005 indicate the statistical significance compared to the controls.