Table 1. Demographic and clinical characteristics of patients in the derivation and validation cohorts.

Variables	Derivation cohort (n = 1035)	Validation cohort (n = 186)	p- value
Age in years, mean (SD)	65 (20)	69 (17)	0.002*
Male sex, n (%)	506 (49)	109 (59)	0.015#
ICU patients	149 (14)	40 (22)	0.016#
SAPS II, mean (SD)	29 (13)	35 (15)	<0.003*
Total SOFA, median (IQR)	1 (0–3)	2 (1–4)	<0.001&
Hospital mortality, n (%)	138 (13)	34 (18)	0.085#

SD – standard deviation, IQR – interquartile range. SOFA – Sepsis-related Organ Failure Assessment

^*Independent samples t-test,

^#Pearson Cui-square Test;

^&Independent samples median test.