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. 2013 Jul 24;8(7):e70806. doi: 10.1371/journal.pone.0070806

Table 6. Risk of hospital mortality according to the total score of each PIRO component.

Predisposition Insult Response Organ
Risk of mortality classification P1 Low P2 Medium P3 High I1 Low I2 High R1 Low R2 High O1 Low O2 High
Score (total sum of points) 0–2 3–4 ≥5 0–1 2 0–3 ≥4 0 ≥1
Derivation Cohort
Hospital mortality (n = 138) 3% 11% 30% 11% 19% 11% 47% 5% 17%
Percentage of total patients (n = 1035) 45% 25% 30% 69% 31% 93% 7% 33% 67%
Validation Cohort
Hospital mortality (n = 34) 3% 16% 33% 16% 26% 12% 52% 0% 24%
Percentage of total patients (n = 186) 36% 24% 40% 73% 27% 84% 16% 24% 76%