Table 1. Effect of CD-3 on NDEA/CCl4-induced hepatocarcinogenesis.
Group | Mice with lesions/ total of mice | Incidence (%)a | Multiplicity | Initial body weight (gm) | Final body weight (gm) | Liver weight (gm) | Relative liver weight (gm) |
---|---|---|---|---|---|---|---|
Group 1 | 0/10 | 0.0 | 0.00 | 26.38 ± 0.19 | 27.51 ± 0.17 | 1.49 ± 0.009 | 5.43 ± 0.024 |
Group 2 | 6/6 | 100 | 4.83 | 26.19 ± 0.15 | 25.26 ± 0.14 | 1.90 ± 0.013 | 7.54 ± 0.078 |
Group 3 | 2/9 | 22.22 | 1.5* | 26.17 ± 0.12 | 26.48 ± 0.13* | 1.59 ± 0.049* | 6.02 ± 0.18* |
Group 1: Control; Group 2: NDEA/CCl4; Group 3: NDEA/CCl4/CD-3. Values are presented as mean ± SEM of all animals per group. a percent mice with tumor; * Significantly different from group 2 (P < 0.001).