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. 2013 Jul 24;8(7):e68710. doi: 10.1371/journal.pone.0068710

Table 1. Effect of CD-3 on NDEA/CCl4-induced hepatocarcinogenesis.

Group Mice with lesions/ total of mice Incidence (%)a Multiplicity Initial body weight (gm) Final body weight (gm) Liver weight (gm) Relative liver weight (gm)
Group 1 0/10 0.0 0.00 26.38 ± 0.19 27.51 ± 0.17 1.49 ± 0.009 5.43 ± 0.024
Group 2 6/6 100 4.83 26.19 ± 0.15 25.26 ± 0.14 1.90 ± 0.013 7.54 ± 0.078
Group 3 2/9 22.22 1.5* 26.17 ± 0.12  26.48 ± 0.13*  1.59 ± 0.049* 6.02 ± 0.18*

Group 1: Control; Group 2: NDEA/CCl4; Group 3: NDEA/CCl4/CD-3. Values are presented as mean ± SEM of all animals per group. a percent mice with tumor; * Significantly different from group 2 (P < 0.001).