Table 4. Effect of CD-3 on oxidative stress markers in mouse liver.

Parameters	Group 1	Group 2	Group 3
MDA (nmol/ mg protein)	3.38 ± 0.065	17.71 ± 0.32*	7.44 ± 0.31*
Nitrite (µg/mg protein)	0.500 ± 0.017	1.80 ± 0.031*	0.86 ± 0.025*
CAT (U/ mg protein)	5.26 ± 0.079	1.19 ± 0.038*	4.18 ± 0.053*
SOD (U/ mg protein)	18.55 ± 0.50	7.42 ± 0.85*	13.91 ± 0.55*
Total thiols	17.12 ± 0.20	6.39 ± 0.25*	13.59 ± 0.23*
GSH (nmol/ mg protein)	5.31 ± 0.16	1.69 ± 0.028*	3.98 ± 0.13*
PrPr-SH	11.81 ± 0.24	4.7 ± 0.23*	9.59 ± 0.23*
GST (GSH-CDNB conjugate/min/mg protein)	31.85 ± 0.70	9.59 ± 0.28*	24.26 ± 0.47*
GPx ((nmol NADPH oxidized/min/mg protein)	14.14 ± 0.40	3.95 ± 0.13*	9.28 ± 0.24*
GR ((nmol NADPH oxidized/min/mg protein)	15.15 ± 0.19	3.13 ± 0.13*	9.84 ± 0.26*

Group 1: Control; Group 2: NDEA/CCl₄; Group 3: NDEA/CCl ₄/CD-3. Data represent the means ± SEM in each group. *P < 0.001 versus vehicle treated and NDEA/CCl₄ or NDEA/CCl₄/CD-3. Comparisons were made between Group 1 and Group 2 mice and between Group 2 and Group 3 mice.