Table 1. Representation of the top network and functional pathways using IPA approach.

	Eng+/+ 16 Gy	Eng+/− 16 Gy	Eng+/+ 16 Gy	Eng+/− 16 Gy
	Network	Network	Functional pathway	Functional pathway
4 weeks	Nerv.system devlp. & funct. (51)	Hematl. system devlp.& funct. (36)	1. Inflammatory response	1. Cell-to-cell signlg.& inter.
			2. Immunological disease	2. Cell death
20 weeks	Inflammatory response (49)	Inflammatory response (40)	1. Inflammatory response	1. Cancer
			2. Cell-to-cell signlg.& inter.	2. Cardio.system devlp.& funct.
40 weeks	Lipid metabl, Molecl. Transp. (49)	Cellular movement (36)	1. Cancer	1. Tissue development
			2. Genetic disorder	2. Antigen presentation

Top networks for 4, 20 and 40 weeks after 16 Gy irradiation of Eng^+/+ and Eng^+/− mice. Numbers in brackets represent the network score, which is explained in material and methods. The first two functional pathways for 4, 20 and 40 weeks after 16 Gy irradiation of Eng^+/+ and Eng^+/− mice are also shown. Nerv.system devlp. & funct. : Nervous system development and function; Lipid metabl, Molecl. Transp.: Lipid metabolism, Molecular transport; Hematl. system devlp.& funct.: Hematological system development and function; Cell-to-cell signlg.& inter.: Cell-to-cell signaling and interaction; Cardio.system devlp.& funct.: Cardiovascular system development and function.