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. 2013 Jul 24;8(7):e68838. doi: 10.1371/journal.pone.0068838

Table 3. Cox proportional hazard regression analyses for overall survival.

Clinical features Univariable analysis*
Multivariable analysis*
HR (95% CI) P value HR (95% CI) P value
Gender 1.143 (0.740-1.764) 0.547
Age 1.000 (0.977-1.025) 0.981
Differentiation 1.565 (1.080-2.268) 0.018 1.408 (0.964-2.057) 0.077
Tumor invasion 1.526 (1.125-2.072) 0.007 1.412 (0.964-2.069) 0.077
LN metastasis 2.059 (1.338-3.168) 0.001 1.980 (1.017-3.856) 0.045
CRNN 0.375 (0.232-0.607) <0.001 0.429 (0.263-0.701) 0.001
*

HR = hazard ratio; CI = confidence interval.